Fertility Preservation in Breast Cancer Patients
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CitationMarin, L., Turan, V., & Oktay, K. (2022). Fertility Preservation in Breast Cancer Patients. Female and Male Fertility Preservation, pp. 185-198. https://doi.org/10.1007/978-3-030-47767-7_14
Breast cancer is the most common malignancy in women as it currently represents 15.2% of all new cancer cases in the United States with 268,600 estimated new cases in 2019 . Under 45 years of age, the percentage of new cases is 10.3% as it is the most common of all in women of childbearing age. Due to the increasingly advanced diagnostic and therapeutic techniques, the mortality rate remains low in recent years. For stages I and II, the 5-year survival is estimated to be respectively 95% and 85–70% (depending on whether they are IIA and IIB), while in advanced stages, survival rates are between 18 and 52% (for stages IIIA and B) . Because the number of young cancer survivors is increasing and as women tend to have children in later reproductive ages, increasing attention has been paid to chemotherapy-related ovarian toxicity . Most women with breast cancer are likely to undergo neoadjuvant or adjuvant chemotherapy that may result in premature ovarian failure and infertility [3–5].