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Vitamin B kompleksinin fotodinamik terapiyle kolon kanserine etkisi
(Süleyman Demirel Üniversitesi, 2023)Amaç: Kolon kanserleri, hastanın yaşam kalitesini derinden etkileyen ve çeşitli komplikasyonlarla ilişkili kronik ölümcül bir hastalıktır. Vitamin B kompleksi, gıda takviyesi olarak alındığında olumlu anti-inflamatuar ... -
Exploring the molecular mechanism of linagliptin in osteosarcoma cell lines for anti-cancer activity
(Elsevier, 2023)Background: Finding new applications for widely used current drugs is a fast and effective technique for discovering new anticancer chemicals. Osteosarcoma (OS), the most prevalent form of bone cancer, has several side ... -
Determination of bisphenol a and phthalate levels in wastewater samples
(İstanbul Üniversitesi, 2022)Objective: The use of endocrine-disrupting chemicals (EDCs) such as bisphenol A (BPA) in plastics manufacturing, agriculture, livestock, and paint manufacturing increas daily. The water treated in wastewater treatment ... -
Determination of Rh type and gender using circulating cell-free fetal DNA in early pregnancy of Rh negative women in Turkey
(Elsevier, 2023)Introduction: Choosing the right clinical approach for early and reliable diagnosis/screening is becoming more important day by day. The aim of the study was to determine the early RhD type with cff-DNA obtained from ... -
Photodyanamic therapy in the cervical cancer
(Özgür Yayınları, 2023)Cancer is one of the most common and feared illnesses in modern society. Its prevalence has been gradually rising in recent years. The fourth most common malignancy in women worldwide is cervical cancer (CC). Surgery, ... -
Novel targeted therapeutic approaches to cancers
(Özgür Yayınları, 2023)Kanser, modern toplumun en yaygın ve korkulan hastalıklarından biridir. Son yıllarda insidansı giderek artmaktadır. Kanserin moleküler özelliklerinin anlaşılmaya başlamasıyla birlikte çalışmalar hedefe yönelik tedaviler ... -
Genetic deviation associated with photodynamic therapy in hela cell
(Elsevier, 2023)Photodynamic therapy (PDT) is a crucial method that is used in cancer treatment. Entering the program for PDT selection today gives a new direction. The main therapeutic effect is the production of singlet oxygen (1O2), ... -
Molecular mechanisms of heat shock proteins in distinct diseases
(Scientific Scholar, 2023)Heat shock proteins (HSPs) modulate the molecular mechanics of cells and cellular systems. Properly folded proteins are required for cellular processes and organisms use molecular mechanics to keep substrate proteins in ... -
Kolorektal kanserde kullanılan biyobelirteçler
(Kolorektal Cerrahi Hastalıklar, 2020)Kolorektal kanser (KK), hem erkek hem de kadınlarda meydana gelen en yaygın ve ölümcül malignitelerden biri olarak kabul edilir. Yaygın prevalansı, KK için yeni tanısal ve prognostik biyobelirteçlere olan ihtiyacı ... -
P. aeruginosa bakterisinin vitamin B kompleksi ve kırmızı lazer kullanılarak inaktive edilmesi
(Süleyman Demirel Üniversitesi, 2022)Son yıllarda anti-bakteriyel direnç olgusu, bakterilerin neden olduğu hastalıklarla mücadelede daha fazla sorun haline gelmiştir. Biz bu çalışmayla, açık yara ve yanıkların fırsatçı patojeni olan Pseudomonas aeruginosayı ... -
Role of p53 in human cancers
(IntechOpen, 2022)TP53 codes tumor protein 53-p53 that controls the cell cycle through binding DNA directly and induces reversible cell-cycle arrest. The protein activates DNA repair genes if mutated DNA will be repaired or activates ... -
The effects of thymoquinone on steroid-induced femoral head osteonecrosis: An experimental study in rats
(Turkish Joint Diseases Foundation, 2022)Objectives: In this study, we aimed to evaluate the antioxidant, antiapoptotic, osteoblastic and hypolipidemic effects of thymoquinone (TQ) treatment on the steroid-induced osteonecrosis of femoral head (ONFH) model in ... -
Biyolojik tanıma elemanlarından proteinoidler kullanılarak empedans ölçüm yaklaşımıyla bakterilerin tespiti
(Bilecik Şeyh Edebali Üniversitesi, 2021)Günümüz dünyasında gelişen teknoloji ile su, gıda ve çevresel kirliliğin artmasıyla bu temel ihtiyaçların sağlık kontrolü oldukça zorlayıcıdır. Bu tür eksiklerin giderilmesi üzerine bir çalışma olmuştur. Bu amaçla iki temel ... -
Aza-BODIPY photosensitizer substituted with phthalonitrile groups: Synthesis, photophysical properties and in vitro tests for breast cancer
(Elsevier, 2023)In photodynamic therapy (PDT), reactive oxygen species (ROS) are generated through dynamic interactions between light of a specific wavelength, a photosensitizer (PS) and molecular oxygen. Nowadays, there has been an ... -
The effect of different storage conditions on the migration of chemicals from polyethylene terephthalate and polycarbonate bottles to water
(İstanbul Üniversitesi, 2022)Objective: Polyethylene terephthalate (PET) and polycarbonate (PC) bottles have been used widely in the last years for the consumption of water and the increased use of these chemicals has raised many concerns regarding ... -
Ozone combined with doxorubicin exerts cytotoxic and anticancer effects on Luminal-A subtype human breast cancer cell line
(Associação Médica Brasileira, 2022)Objective: We aimed to examine the potential anticancer effects of ozone applied after chemotherapeutic treatment with different concentrations of doxorubicin in Luminal-A subtype of human breast cancer cell line (MCF-7) ... -
The effects of zinc(II)phthalocyanine photosensitizers on biological activities of epitheloid cervix carcinoma cells and precise determination of absorbed fluence at a specific wavelength
(Elsevier, 2022)Photodynamic therapy (PDT) is an alternative way to treat the cancer non-surgically with minimum harm, in which a specific light and light sensitive photosensitizer (PS) is used. This study deals with the utilization of ... -
Liposomes loaded with activatable disulfide bridged photosensitizer: Towards targeted and effective photodynamic therapy on breast cancer cells
(AMG Transcend Association, 2022)The motivation of the current study is to develop a strategy providing targeted and effective photodynamic therapy (PDT) on breast cancer cells by eliminating the limitations of PDT. For this purpose, a disulfide bridged ...
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