Browsing Temel Tıp Bilimleri Bölümü Koleksiyonu by Issue Date
Now showing items 1-20 of 28
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Immunohistochemical determination of mTOR pathway molecules in ovaries and uterus in rat estrous cycle stages
(University of Murcia, 2020)mTOR is a member of the PI3K/Akt/mTOR signaling pathway that participates in cell growth, proliferation, protein synthesis, transcription, angiogenesis, apoptosis and autophagy. mTOR and MAPK pahways are two important key ... -
Self- and parent-rated quality of life in school aged children with ADHD: The impact of common comorbid psychiatric disorders and motor proficiency
(Aves, 2020)Background: The aim of the study was to investigate the relationship between the clinical key factors, that is, ADHD symptom severity, comorbidity and motor skill level, and the quality of life perceived by the child and ... -
Female circumcision debate: A muslim surgeon's perspective
(AVES, 2021)In this study, we aimed to address female circumcision (FC) from sociocultural, medical, ethical, and religious/Islamic perspectives through the understanding of a Muslim surgeon. FC is performed primarily in Africa today, ... -
Choline or CDP-choline restores hypotension and improves myocardial and respiratory functions in dogs with experimentally-Induced endotoxic shock
(Elsevier, 2021)Endotoxin shock is associated with severe impairments in cardiovascular and respiratory functions. We showed previously that choline or cytidine-5 '-diphosphocholine (CDP-choline) provides beneficial effects in experimental ... -
Comparison of reference intervals derived by direct and indirect methods based on compatible datasets obtained in Turkey
(Elsevier, 2021)Background: Indirect derivation of reference intervals (RIs) from the laboratory information system (LIS) has been recently pursued. We aimed at evaluating the accuracy of indirectly predicted RIs compared to the RIs ... -
Nesfatin-1 and neuronostatin neurons are co-expressed with glucocorticoid receptors in the hypothalamus
(Taylor and Francis, 2021)Nesfatin-1 and neuronostatin in the central nervous system participate in regulating stress responses. Glucocorticoid hormones affect the brain through glucocorticoid receptors (GR). We investigated in the rat the possibility ... -
Immunolocalization of FOXP3, JAK1 and STAT5in preeclamptic, intrauterine growth restricted and gestational diabetic human placentas
(Abdurrahman Hamdi İnan, 2021)Objective: The aim of the study to show the relation of T cells in placental villous fragments with FOXP3,JAK1 and STAT5 receptors in different conditions such as GDM, PE and IUGR placental tissues. Materials and Methods: ... -
Tıbbi genetiğin tarihi
(Hayat Sağlık ve Sosyal Hizmetler Vakfı, 2021)Evelyn Fox Keller; Mendel’in kalıtıma ilişkin bulgularının yeniden keşfi ile başlayıp, İnsan Genom Projesinin (İGP) ilk taslağının tamamlanmasının arifesinde sona eren 20. yüzyılın, “genin yüzyılı” olduğunu söylemektedir ... -
CRISPR/Cas-9 ile soy hattına yönelik genetik müdahale: etik tartışmaların değerlendirilmesi
(Ortadoğu Reklam Tanıtım Yayıncılık, 2021)CRISPR/Cas-9 teknolojisinin programlanabilecek şekilde geliştirilmesinin üzerine, tıp etiğinin en çok tartışılan konularından biri genetik müdahaleler olmuştur. Somatik ve soy hattına yönelik genetik müdahaleler şeklindeki ... -
The apoptotic efficacy of succinic acid on renal cancer cell lines
(Springer, 2021)Recently, studies on the effects of non-toxic substances on cancer prophylaxis have gained value as an alternative to existing treatment options. Current studies have shown that succinic acid or its derivatives exhibit ... -
Can we consider embryos solely as biological material?
(Scholars' Press, 2021)Traditionally, bioethical discussions about embryo research tend to resort to moral status arguments. Bioethicists arguing in favor of embryo research who embrace what we call the “none-approach” use psychological or ... -
An ethical reflection on the heritability argument in the germline genetic intervention debate
(Consortium of Islamic Medical Colleges, 2021)Germline genetic intervention (GGI) has been one of the most discussed topics within the bioethics literature since 2012, when the programming of CRISPR/Cas9 for a specifically targeted gene region has become possible. ... -
Antik dönemden günümüze dünyada ve ülkemizde üroloji alanındaki gelişmelerin tarihçesi
(Hayat Sağlık ve Sosyal Hizmetler Vakfı, 2021)Her ne kadar ürolojinin ayrı bir disiplin olarak tesisi 19. yüzyılın ikinci yarısına rastlarsa da, bugün ürolojinin alanına giren organlar, hastalıklar ve tedaviler prehistorik dönemden beri genel tıbbın ve daha sonra ... -
Günümüz müslüman ülke ve topluluklarında salgın hastalıklara yaklaşım: COVID-19 ve FIMA örneği
(İbn Haldun Üniversitesi Yayınları, 2021)Bir koronavirüs fırtınası koptugidiyor. Dünya Sağlık Örgütü’nün “küresel salgın” tanımı yaptığı, dünyanın hemen her köşesinde paniğe sebep olan, bulaşma riski çok yüksek ve henüz tedavisi bulunmayan bir salgın bir yıla ... -
A novel differential diagnosis algorithm for chronic lymphocytic leukemia using immunophenotyping with flow cytometry
(Elsevier, 2021)Introduction: The availability of a clinical decision algorithm for diagnosis of chronic lymphocytic leukemia (CLL) may greatly contribute to the diagnosis of CLL, particularly in cases with ambiguous immunophenotypes. ... -
Cysteine challenge test as a novel diagnostic tool to distinguish oral halitosis
(Wiley, 2021)Background: The cysteine challenge test is often used to check the H2S production capacity of the mouth. Patients with oral halitosis group (n = 305) or non-oral halitosis group (n = 191) and healthy individuals (control ... -
Effect of a decellularized omentum scaffold with combination of mesenchymal stem cells and platelet-rich plasma on healing of critical-sized bone defect: A rat model
(MDPI, 2021)The high costs and extensive time needed for the treatment of critical-sized bone defects are still major clinical concerns in orthopedic surgery; therefore, researchers continue to look for more cost and time-effective ... -
Chakrabarty, moore ve insan genleri brca1/2: Abd’de gen patentlerinin hukukî geçmişi, Avrupa Birliği ve Türkiye’deki düzenlemeler ve bir biyoetik değerlendirme
(Legal Yayıncılık, 2021)Yirminci yüzyıl sonlarına kadar uzun yıllar canlı varlıkların patentlenemeyeceği düşünülmüşken, 1970’lerden itibaren Amerikan mahkemelerinde biyolojik materyaller için yapılan patent başvuruları lehine alınan tarihî ...
