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Yayın Push-out bond strength of fiber posts to irradiated and non-irradiated intraradicular dentin(Springer Nature, 2022) Başer Can, Elif Delve; Barut, Güher; Işık, Vasfiye; Algül, Emriye; Yaprak, Gökhan; Can, EsraObjectives The aim of this study is to evaluate the infuence of ionizing radiotherapy on the resin-dentin interface in endodontically treated teeth restored with fber posts using a dual-cure resin cement performed with the etch-and-rinse (ER) and self-etch (SE) approaches in terms of push-out bond strength (MPa), and to analyze the post/cement/dentin interface using scanning electron microscopy (SEM). Materials and methods Seventy-six single-rooted human teeth were used and randomly assigned into two main groups (n=38): one non-irradiated group (NoRad) and one group subjected to a cumulative radiation dose of 60 Gy (Rad). All root canals were instrumented and were further subdivided into two subgroups (n=19) following the adhesive approach: ER (RadER; NoRadER) and SE (RadSE; NoRadSE) used for fber post luting with the universal adhesive and dual cure resin cement. Each root was sectioned perpendicularly to its long axis and sections from the middle third of the roots were chosen for SEM analysis and push-out bond strength test. Two-way ANOVA with post hoc Tukey tests and a dummy variable linear regression analysis were used for data analysis. Results Regardless of the adhesive approach, push-out bond strength in irradiated teeth resulted in signifcantly lower values than non-irradiated teeth (p=0.0001). There were no signifcant diferences between the ER and SE approaches in non-irradiated teeth (p=0.955), whereas the ER approach showed signifcantly higher bond strengths than the SE approach in irradiated teeth (p=0.0001). Conclusions Ionizing radiotherapy resulted in dentin structure disruption and negatively afected the push-out bond strength of fber posts to intraradicular dentin. The reduction in bond strength was also more signifcant with the SE approach than with the ER approach. Clinical relevance The alterations resulting from root dentin irradiation seem to infuence adhesive systems bond strength to dentin, as these changes contribute to lower push-out bond strength in irradiated groups before fber post luting. Thus, clinicians should prepare patients with a reasonable restorative treatment plan prior to radiotherapy and simultaneously initiate a preventive program during radiotherapy.