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    Muscle hydatid diseases: percutaneous treatment with Örmeci technique
    (MediHealth Academy Yayıncılık, 2022) Örmeci, Necati; Asiller, Özgün Ömer; Yağcı, Cemil; Örmeci, Tuğrul; Ellik, Zeynep; Kalkan, Çağdaş; İlhan, Atilla
    Aim: To present results of percutaneous treatment with Örmeci technique for muscle hydatid diseases. Material and Method: Twelve patients (9 male, 3 female) with 16 hydatid cysts (10 CE Type 1, 6 CE Type3B) were treated by percutaneous treatment with Örmeci technique. The percutaneous puncture was performed under sonographic guidance using a 22-gauge Chiba needle as a one-step procedure in CE type 1 and 3A. However, two to six Chiba needles according to size of the cysts were used in different locations at the same time in the cyst of CE type 2, and 3B). For every 1 cm of the long diameter of the cyst lesion, 3cc of fluid from the cysts was aspirated, which was almost the same amount of cc in volume for the CE type 1 and CE type 3A hydatid cysts. A 2cc of pure alcohol (96 %) and 1cc of polidocanol 1% (ethoxysclerol 1%, Kreussler Pharma, Wiesbaden, Germany) were injected into the cysts right after the aspiration of CE type 1 and type 3A, without the aspiration of CE type 2 and 3B, for each centimeter of the long diameter of the cysts. The total amount of pure alcohol and polidocanol were injected equally among the CE type 2 and type 3B cyst’s needles. It was waited for five minutes for all scolexes to be killed and the needle/or needles were taken back. The patients with hydatid disease were followed up mean 34.75 ±14.39 (maximum 65-minimum 15) months. Findings: Fifteen out of 16 hydatid cysts (93.75%) cured. We had two complications of treatment. One patient had an abscess in the cyst after the percutaneous treatment. After the percutaneous drainage, patient was cured well, and he had no symptoms during the follow up. Another patient had torpidity in his leg after the treatment. After three months, he had no symptoms. In Conclusion, Percutaneous treatment with Örmeci technique is outpatient based, successful, safe, repeatable, cheap and It can be used as an alternative treatment in selected patients.
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    Noncontrast-enhanced MRI-based noninvasive score for portal hypertension (CHESS1802): An international multicenter study
    (Xia & He Publishing Inc., 2021) Liu, Yanna; Tang, Tianyu; Örmeci, Necati; Huang, Yifei; Wang, Jitao; Li, Xiaoguo; Li, Zhiwei; An, Weimin; Liu, Dengxiang; Zhang, Chunqing; Liu, Changchun; Liu, Jinqiang; Liu, Chuan; Wang, Guangchuan; Mosconi, Cristina; Cappelli, Alberta; Bruno, Antonio; Akçalar, Seray; Çelebioğlu, Emrecan; Üstüner, Evren; Bilgiç, Sadık; Ellik, Zeynep; Asiller, Özgün Ömer
    Background and Aims This study aimed to determine the performance of the non-invasive score using noncontrast-enhanced MRI (CHESS-DIS score) for detecting portal hypertension in cirrhosis. Methods In this international multicenter, diagnostic study (ClinicalTrials.gov, NCT03766880), patients with cirrhosis who had hepatic venous pressure gradient (HVPG) measurement and noncontrast-enhanced MRI were prospectively recruited from four university hospitals in China (n=4) and Turkey (n=1) between December 2018 and April 2019. A cohort of patients was retrospectively recruited from a university hospital in Italy between March 2015 and November 2017. After segmentation of the liver on fat-suppressed T1-weighted MRI maps, CHESS-DIS score was calculated automatically by an in-house developed code based on the quantification of liver surface nodularity. Results A total of 149 patients were included, of which 124 were from four Chinese hospitals (training cohort) and 25 were from two international hospitals (validation cohort). A positive correlation between CHESS-DIS score and HVPG was found with the correlation coefficients of 0.36 (p<0.0001) and 0.55 (p<0.01) for the training and validation cohorts, respectively. The area under the receiver operating characteristic curve of CHESS-DIS score in detection of clinically significant portal hypertension (CSPH) was 0.81 and 0.9 in the training and validation cohorts, respectively. The intraclass correlation coefficients for assessing the inter- and intra-observer agreement were 0.846 and 0.841, respectively. Conclusions A non-invasive score using noncontrast-enhanced MRI was developed and proved to be significantly correlated with invasive HVPG. Besides, this score could be used to detect CSPH in patients with cirrhosis.
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    Percutaneous treatment with the Örmeci technique of cystic echinococcosis: experience of single center
    (MedCrave, 2020) Örmeci, Necati; Asiller, Özgün Ömer; Kalkan, Çağdaş; Ellik, Zeynep; Çalışkan Kartal, Aysun; Er, Ramazan Erdem; Elhan, Atilla Halil; Örmeci, Tuğrul
    Background: Hydatid disease is caused by the larval stage of Echinococcus Granulosis which is an important public health and economic problem. The treatment of hydatid cyst is not optimal yet. Objective: We want to show the Ormeci technique is the one of the best treatment options of hydatid cyst. Materials and methods: Five hundred thirty-seven patients with seven hundred and sixteen hydatid cysts had been treated by percutaneous way using the Ormeci technique since 1991. The percutaneous puncture was performed under sonographic guidance using a 22-gauge Chiba needle as a one-step procedure in CE type 1 and 3A. However, two to six Chiba needles were used in different locations at the same time in CE type 2b, 2c and 3B cysts. The mean follow-up time was 51.24±62.99 (minimum 3.00, maximum 340.00) months. Results: This technique increased the cure rate of CE type 2 and 3B hydatid cysts up to 91.7% without recurrences. The success rate for all types of cysts treated was 95% without mortality. The technique had less morbidity (8.86%) without fistula and abscess. Conclusion: Ormeci technique can be safely and successfully used for the treatment of all kinds of active hydatid cysts.