İstanbul Sağlık ve Teknoloji Üniversitesi Kurumsal Akademik Arşivi
DSpace@İSTÜN, Üniversite mensupları tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Effectiveness of fissure sealants following different silver fluoride application protocols in MIH-affected molars: Randomized clinical study
(Springer Nature Link, 2026) Çayıroğlu, Nagihan; Ballıkaya, Elif; Erbaş Ünverdi, Gizem; Çehreli, Zafer Cavit
Objectives To compare the clinical efficacy of glass ionomer sealants (GIS) and resin-based sealants (RBS) applied imme diately or one week after silver fluoride (SF) application to permanent molars affected by molar incisor hypomineralization (MIH) in children at high risk for caries. Methods A total of 216 MIH-affected molars (ICDAS 1–2) from 102 children aged 6–14 years were randomly allocated to six groups: Resin- or glass ionomer–based fissure sealants were placed either one week after the application of silver fluoride or during the same clinical session. In the same-visit protocols, sealants were applied immediately after silver fluoride treatment, either following gentle blot drying with cotton or after immediate rinsing. Hypersensitivity, caries progression, and sealant retention were assessed at 1, 6, and 12 months. Hypersensitivity was evaluated using the Schiff Cold Sensitivity Scale (SCASS). Sealant performance was analyzed using modified USPHS criteria. Statistical analyses included Fisher’s Exact Test and the Friedman test. Results Full retention was achieved in all resin-based sealant groups, while the lowest retention rate (88.9%) was recorded in the glass ionomer sealant group applied one week after silver fluoride. Caries occurred in 2.8% of teeth and was confined to three groups: glass ionomer sealants placed one week after silver fluoride, resin-based sealants applied immediately following blot drying, and glass ionomer sealants applied immediately after rinsing. All other groups showed complete clinical success. No statistically significant differences were found among groups regarding caries prevention (p=1.000) or sealant retention (p=0.062). Hypersensitivity decreased significantly over time in all groups. Conclusion Resin-based and glass ionomer fissure sealants placed either one week after silver fluoride application or immediately following treatment, using rinsing or blot-drying protocols, showed similar outcomes over a 12-month follow-up period in terms of caries prevention and reduction of hypersensitivity. Nonetheless, within the limitations of this study, sealants placed immediately following silver fluoride application demonstrated a greater frequency of discoloration. Clinical significance Both glass ionomer and resin-based fissure sealants can be successfully applied either immediately or one week following silver fluoride treatment to provide protection for MIH-affected permanent molars. Clinical trials registration number NCT06641011.
Functional and surgical outcomes of ventral mesh rectopexy in male patients with rectal prolapse: A nationwide multicenter retrospective cohort study by the pelvic floor working group of the Turkish society of colon and rectal surgery (TSCRS)
(Springer Nature Link, 2026) Gültekin, Fatma Ayça; Balcı, Bengi; Kuzeyli Yıldırım, Yasemin; Arslan, Çiǧdem; Yaşar, Necdet Fatih; Bisgin, Tayfun; Bayraktar, Adem; Zenger, Serkan; Şengül, Neriman; Bulut, Türker Mehmet
Background The indications and outcomes of ventral mesh rectopexy (VMR) in the treatment of rectal prolapse in males have been minimally addressed in the literature. This study aimed to evaluate the demographics, clinical characteristics, and surgical outcomes associated with VMR in male patients. Methods This nationwide retrospective cohort study included male patients who underwent VMR at centers performing pelvic floor surgery across Turkey. Clinical and surgical characteristics were obtained, and functional outcomes were evalu ated using Cleveland Clinic Incontinence score (CCIS) and Altomare Obstructed Defecation Syndrome (ODS) scores at the pre- and postoperative periods. Results Forty-one male patients (mean age, 45.4 years; mean BMI, 25.6 kg/m2 ) underwent VMR (2 open, 5 robotic, and 34 laparoscopic). The cohort comprised 11 patients with internal rectal prolapse (IRP) and 30 with external rectal prolapse (ERP). The overall complication rate was 17.1% (2.4% related to mesh), with a 12% recurrence rate. The median follow-up was 33 (6–127) months. The recurrence rate was 36.4% for IRP patients and 3.3% for ERP patients (p=0.014). Significant improvements were observed in the CCIS (preoperative: 6.1±4.8; postoperative: 2.8±3.3, p=0.005) and Altomare ODS (preoperative: 11.9±4.6; postoperative: 7.26±5.8, p<0.001). Conclusions In this nationwide retrospective cohort study, VMR was associated with favorable functional outcomes in males. Recurrence rates were significantly higher in those with internal rectal prolapse. As sexual function was not systematically assessed, prospective studies with standardized patient-reported outcomes are warranted.
Artificial intelligence in medical education: Curriculum design, assessment models, and educational infrastructure across undergraduate and residency training – A narrative review
(Turkish Society of Cardiology, 2026) Göçer, Hakan; Durukan, Ahmet Barış; Özyüksel, Arda
Artificial intelligence (AI) is rapidly becoming an integral part of everyday clinical practice, including cardiology and cardiovascular surgery. As AI increasingly influences diagnostic and therapeutic decisions, physicians are expected to interact with these systems in a critical, safe, and ethically grounded manner. This narrative review aims to explore how AI can be systematically integrated into undergraduate and residency medical education, with a particular focus on curriculum design, teaching strategies, assessment models, and educational infrastructure, while considering the context of the Turkish medical education system. A narrative synthesis of international medical education literature, policy documents, and institutional reports was conducted without quantitative meta-analysis. The review was guided by the principles of human-in-the-loop clinical reasoning, ethical AI use, and patient safety. Effective integration of AI into medical education requires a longitudinal and staged curriculum spanning preclinical, clinical, and residency training. Assessment strategies must explicitly address AI-assisted decision-making and be supported by transparent institutional policies governing AI use in examinations, as well as by secure, regulation-compliant digital infrastructure. Educational approaches should encourage learners to critically appraise and contextualize AI outputs rather than accept them uncritically. The reviewed literature supports a competency-based educational framework that integrates AI literacy, ethical reasoning, and context-aware clinical judgment. AI education should be viewed as a core clinical competency that strengthens rather than replaces human judgment. Particularly in high-risk cardiovascular disciplines, a standardized, ethics-centered, and competency-based educational framework is essential to prepare future physicians for AI-augmented healthcare environments.
Safety, feasibility and indications of transabdominal oocyte pick-up: Initial experience
(World Scientific, 2026) Turan, Volkan; Öktem, Özgür
Although the transvaginal route is the preferred method for the oocyte retrieval procedure, the transabdominal (TA) route may be preferred in certain conditions. In this opinion we presented our experience with TA oocyte pick-up in 101 patients across several different indications and assessed the safety of the procedure.
The use of bispectral index for monitorization of the depth of sedation in procedural sedoanalgesia in the emergency department
(Bayrakol Medical Publisher, 2026) Gökdağ, Eren; Sarı Doğan, Fatma; Yılmaz, Sarper
Aim: To determine the effectiveness of the Bispectral Index (BIS) measurement as an objective criterion for measuring the depth of sedation in the emergency department (ED) by comparing it with the Modified Ramsey Sedation Scale (MRSS), which is a clinical scale for measuring sedation depth. Methods: In this study, the compatibility of BIS values and MRSS values at the moment when the patients reached clinically appropriate sedation depth for intervention in those requiring sedation-analgesia in the ED due to extremity trauma were compared. Results: No statistically significant correlation was found between patients’ initial MRSS scores at the time of intervention and either their initial or minimum BIS values (p>0.05). A moderate negative correlation (r=-0.432, p=0.022) was observed between the MRSS values and the minimum BIS readings. No statistically significant difference was observed in minimum BIS values based on the sedative agent administered (p>0.05). Conclusion: In this study, a moderate correlation was found between the lowest BIS values and the MRSS scores corresponding to those BIS values. Although further comprehensive and detailed studies are necessary to establish the limitations and optimal use of BIS monitoring during procedural sedation-analgesia in the ED—especially considering both existing literature and the limitations of this study—BIS appears to be a promising alternative to clinical sedation scales for monitoring sedation depth.
