İstanbul Sağlık ve Teknoloji Üniversitesi Kurumsal Akademik Arşivi
DSpace@İSTÜN, Üniversite mensupları tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Comparison of quadro‑iliac plane block and erector spinae plane block for postoperative analgesia management after single level lumbar discectomy surgery: A randomized, double‑blind, controlled, prospective, multicenter study
(Springer Nature Link, 2025) Turan, Engin İhsan; Otlu Bıyıkoğlu, Büşra; Özen, Volkan; Alver, Selçuk; Umutoğlu, Tarık; Cücü, Oğuzhan; Çevik, Serdar; Çiftçi, Bahadır; Şahin, Ayça Sultan
Purpose Effective postoperative analgesia management is critical for optimizing recovery and patient satisfaction following lumbar discectomy. Erector Spinae Plane Block (ESPB) is an established regional anesthesia technique with proven efficacy, while the novel Quadro-Iliac Plane Block (QIPB) has shown promise as an alternative approach. This study compares the analgesic efficacy, opioid-sparing potential, and safety of ESPB and QIPB in single-level lumbar discectomies. Method This multicenter, prospective, randomized, double-blind study included 60 patients aged 18–65 years undergoing single-level lumbar discectomy. Patients were randomized into ESPB (n=30) and QIPB (n=30) groups. Both blocks were performed at the end of surgery, before the extubation under ultrasound guidance using 40 ml (0.25%) bupivacaine bilater ally. The primary outcome was postoperative pain assessed by the Numeric Rating Scale (NRS) at 12 h. Secondary outcomes included tramadol consumption, rescue analgesia requirements, hemodynamic parameters, and adverse events. Results The primary outcome, 12-h NRS scores, did not differ significantly between groups (p>0.05), indicating similar anal gesic efficacy. Secondary outcomes—including total tramadol consumption (54.00±49.03 mg for ESPB vs. 44.67±44.16 mg for QIPB, p=0.476), need for rescue analgesia, and incidence of nausea and vomiting—were also comparable. No motor block was observed in either group. Conclusion Although QIPB did not demonstrate superiority over ESPB, it was found to be not inferior in analgesic effect and safety outcomes. These findings suggest that QIPB may be a reliable alternative to ESPB in lumbar discectomy procedures.
Impulsivity in parkinson’s disease
(Wolters Kluwer, 2026) Değirmenci, Yıldız; Altınbaş, Kürşat; Keçeci, Hulusi; Bougea, Anastasia; İsmayılov, Rashad; Gourzis, Philippos
Introduction/Aims: Parkinson’s disease (PD) is a neurodegenerative disease characterized by cardinal motor and nonmotor symptoms. Impulse control disorders are common neuropsychiatric manifestations in patients with PD (pwPD) under dopaminergic therapy. However, impulsivity is an underestimated symptom. Hence, the present study aimed to evaluate the impulsivity in pwPD. Methods: Forty‑seven adults who were diagnosed with having PD according to the Queen Square Brain Bank criteria for PD diagnosis and 30 age‑matched healthy controls were enrolled in the study. The sociodemographic data of the study participants and disease characteristics of the patients were recorded. All participants completed the Barratt impulsiveness scale (BIS). BIS scores were statistically analyzed between the groups. Results: The results revealed no significant differences between the patients and controls in terms of age (P > 0.05) or sex (P > 0.05). The total BIS scores were higher in the PD group than in the healthy controls (t = 2.1, P = 0.038). The items of BIS and attentional impulsivity scores were higher in the pwPD than in the controls (t = 2.8, P = 0.005), but there were no statistically significant differences between the groups in terms of motor and nonplanning impulsivity (z = 1.8, P = 0.07; and t = 1.1, P = 0.31, respectively). Discussion: Our results indicate that attentional impulsivity is an important clinical characteristic of pwPD, even in the absence of impulse control disorders. Conclusion: Further studies are required to confirm these findings in view of personalized PD treatment.
Management of plastic wastes: History, current applications, and future perspectives of recycling, upcycling, and reclaiming technologies
(Springer Nature Link, 2026) Alanalp, Mine Begüm; Ergin, Mustafa Fatih; Durmuş, Ali; Das, Alok Prasad; Karakuş, Selcan
Plastic materials possess a variety of structural and physical features and some key characteristics that make them widely used in many applications due to their superior properties such as low density, chemical and mechanical durability, low cost, recyclability, easiness and versatility in processing, thermal and electrical insulating property, colorability. Plastics are used in various applications in many industrial areas and daily-life, including packaging (the largest segment), construction, automotive, electronics, and consumer goods. Since the 1950s, production and consumption of plastics has readily increased, with global production reaching over 370 million metric tons in recent years. This trend is expected to continue, with projections estimating it could reach over 1 billion metric tons by 2030. The highest plastic consumption is found in developed regions like North America, Europe, and parts of Asia. However, emerging economies are rapidly increasing their consumption related to growing industrialization and urbanization in these countries. Overall, while plastics play a crucial role in modern society, their increasing consumption raises important questions about sustainability and environmental health. The rapid increase in plastic production and consumption has led to significant environmental challenges such as pollution, wildlife harm, and waste management issues. An estimated 11 million metric tons of plastic enter the oceans each year. There is a growing push toward a circular economy model, emphasizing the importance of reducing, reusing, and recycling plastics to minimize environmental impact. Managing plastic wastes effectively involves a combination of various strategies aimed at reducing, reusing, recycling, and disposing of plastics in an environmentally responsible manner. Modern societies can significantly reduce plastic waste and its environmental impact, promoting a more sustainable future by integrating these strategies. This chapter comprehensively summarizes and discusses the current applications of recycling, upcycling and reclaiming technologies of plastic wastes. Future perspectives and projections will also be highlighted to manage plastic wastes effectively and establish sustainable development in the world.
Performance and emission characteristics of a single-cylinder diesel engine fueled with a 10% olive pomace oil– diesel blend
(Trakya University, 2025) Tunçer, Erdal; Kaya, Yalçın; Akal, Dinçer
This study investigates the effects of using a 10% olive pomace oil–diesel blend on the performance and emission characteristics of a single-cylinder diesel engine under varying load conditions. The blend was prepared by volumetrically mixing 10% olive pomace oil with standard diesel fuel. The engine was tested under four different load conditions: 25%, 50%, 75%, and 100% of full load capacity.The experimental results revealed that the engine power output decreased by a maximum of only 0.1 kW across all load conditions when compared to standard diesel. This minor reduction indicates that the blend maintains comparable engine performance. Fuel consumption increased by a maximum of 16 ml/h, which is a relatively small difference and within acceptable limits for alternative fuel use. In terms of emissions, carbon monoxide (CO) levels decreased slightly—by approximately 0.01%—across all load conditions, suggesting improved combustion efficiency. However, the reduction in CO was minimal. On the other hand, nitrogen oxides (NOₓ) emissions showed an increase, particularly at higher loads. A maximum increase of 160 ppm was recorded at 75% load, while other conditions showed moderate increases ranging from 55 to 65 ppm. Despite the slight rise in NOₓ emissions, the findings suggest that blending olive pomace oil with diesel at a 10% volumetric ratio can be a viable and sustainable alternative fuel option for diesel engines, with minimal impact on performance and moderate changes in emissions.
Incidence and prognostic factors of isolated para-aortic lymph node metastasis in endometrial cancer: A single-center study
(Minerva Medica, 2025) İbrahimov, Akbar; Boyraz, Gökhan
Para-aortic lymph node metastasis (PALNM) is a key prognostic factor in endometrial cancer (EC). This study aimed to de- termine the incidence and prognostic factors of lymph node metastasis (LNM) and isolated PALNM in endometrioid-type EC patients. METHODS: EC patients treated surgically between 2000 and 2015, staged by FIGO 2009 criteria, were retrospectively analyzed. Included were patients with endometrioid histology grades I-III who underwent pelvic and PALN dissection. Excluded were those without lymph node dissec tion or with non-endometrioid histology. RESULTS: A total of 417 patients met the criteria. Of these, 246 (59%) were grade I, 117 (28.1%) grade II, and 46 (11%) grade III. Pelvic LNM (PLNM) was found in 43 (10.3%), and PALNM in 22 (5.3%). Five patients (1.19%) had isolated PALNM. PALNM was more frequent in patients with stage III, tumors >2 cm, cervical glandular/stromal involvement, deep myometrial invasion, positive peritoneal cytology, adnexal involvement, PLNM, and LVSI. Isolated PALNM was notably higher with adnexal involvement. Independent predictors of PALNM were cer vical glandular involvement and LVSI. Deep myometrial invasion, LNM, PLNM, LVSI, and adnexal involvement were linked to disease-free survival (DFS), while peritoneal cytology, PLNM, and LVSI were linked to recurrence. There was no significant difference in recurrence and DFS between PALNM and isolated PALNM. CONCLUSIONS: Isolated PALNM without PLNM is rare in EC patients but should be assessed for optimal staging and treatment.
