İstanbul Sağlık ve Teknoloji Üniversitesi Kurumsal Akademik Arşivi
DSpace@İSTÜN, Üniversite mensupları tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Psychological impact of the February 6 earthquake on displaced individuals with proximal loss residing in temporary shelters
(Routledge, 2025) Filazoğlu Çokluk, Gülşen; Bal, Fatih; Savaş, Esra
The present study examines the psychological effects of the earthquake that occurred in Turkey on 6 February 2023 on individuals residing in temporary shelters who have experienced losses in their immediate surroundings. The objective of the present research is to elucidate the relationships between post-traumatic stress disorder (PTSD), depression, anxiety, and the subjective impact of the traumatic event. Nine months following the disaster, a survey was conducted among 923 adults aged 25 to 60 residing in temporary shelters in Antakya. Participants completed a series of validated and reliable measurement tools, including the DSM-5 Post-Traumatic Stress Disorder Checklist (PCL-5), the Beck Anxiety Inventory (BAI), the Beck Depression Inventory (BDI), and the Impact of Events Scale (IES). The findings indicate significant and positive correlations between PTSD and all other variables, including the impact of the event, depression and anxiety. The multiple regression analysis revealed that these three variables significantly predicted PTSD symptoms and collectively explained 41% of the variance in PTSD levels. This study emphasizes the cumulative psychological impact of forced displacement and close losses on individuals and underscores the pressing need for culturally sensitive and trauma-informed mental health services in post-disaster intervention processes. The findings contribute to the understanding of trauma dynamics in post-disaster communities and guide the development of targeted mental health policies and psychosocial support programs.
Dijital öğrenme ortamında blackboard ve kütüphane entegrasyonu
(İstanbul Sağlık ve Teknoloji Üniversitesi, 2025) Delibaş, Burak
Dijital öğrenme ortamlarının yükseköğretimdeki önemi her geçen gün artmakta, bu bağlamda öğrenme yönetim sistemleri (LMS) ile kurumsal kaynakların bütünleşik bir yapıda sunulması, öğrenci başarısını ve bilgiye erişimi doğrudan etkilemektedir. Bu çalışma, Blackboard platformu ile üniversite kütüphanesi sisteminin entegrasyon sürecini ele almakta ve bu entegrasyonun öğrenme süreçlerine olan katkılarını değerlendirmektedir. Sunumda, entegrasyonun teknik boyutları, kullanıcı deneyimi üzerindeki etkileri ve akademik başarıya olası katkıları örnek uygulamalar üzerinden tartışılacaktır. Ayrıca, bu entegrasyonun dijital okuryazarlık, bilgi erişim hızı ve kullanıcı memnuniyeti üzerindeki olumlu etkilerine de değinilecektir. Çalışma, dijital kampüs yapısının güçlendirilmesinde kütüphanelerin rolünü vurgularken, sürdürülebilir bir bilgi ekosistemi için iş birliğinin önemine dikkat çekmektedir.
Investigation of the attitudes of faculties of medicine, dentistry, and pharmacy students towards brain drain in terms of future anxiety and satisfaction with life levels
(Bülent DİLMAÇ, 2025) Keçeci, Berra; Gül, Zehra Betül; Özekinci, Ayşe Ekin
The aim of this study is to examine the attitudes of medical, dentistry and pharmacy faculty students towards brain drain in terms of future anxiety and life satisfaction levels. 308 university students enrolled in a foundation university in Istanbul were included in the study. Descriptive statistics, correlation, multiple regression, one-way ANOVA and independent sample t-test analysis were used in the analysis of the data. The regression analysis results showed that hopelessness about the future, future anxiety and life satisfaction were significant predictors of attitudes towards brain drain. According to the independent samples t-test analysis results, it was found that the tendency towards brain drain was higher in male students and students in the clinical education process, while the tendency towards brain drain was lower in dentistry students than in medical and pharmacy students. The study results provide important data for the development of policies to reduce brain drain in the health sector in Türkiye.
Determinants of foreign direct investment in the textile sector: A research with IT2 Fuzzy TOPSIS methodology
(Institute National Cercetare-Dezvoltare Textiles Pielarie, 2025) Şahin, Recep Uğurcan; Nalbant, Kemal Gökhan; Keskin, Abdulkadir; Özdemir, Yavuz; Keskin, Abdurrahman
This study aims to identify the determinants of foreign direct investment (FDI) in the textile sectors in Poland, Romania, Hungary, Slovakia, Czechia and Türkiye. The study assesses these criteria through paired comparisons conducted by experts who have a minimum of 10 years of professional experience in the field and analyses them using the IT2 Fuzzy Technique for Order of Preference by Similarity to the Ideal Solution (TOPSIS) technique. According to the findings, the criteria with the highest degree of importance are national security, inflation rate, patent and trademark protection, transportation networks and market size. On a country-by-country basis, Poland has a higher investment attraction potential compared to other countries according to the criteria of openness, corruption, legal regulations and privatization policies, import and export quotas, education and professional status, renewable energy resources, sustainability, intellectual property protection, patent and trademark protection and national security. Hungary scores highest on import and export quotas and tax rates, while Slovakia stands out on import and export quotas and waste management/environmental regulations. Romania scores highest on profitability and debt financing, labour costs and import and export quotas. Czechia scores highest on inflation rate, political stability, legal regulations and privatization policies, economic incentives, general trade policies, import and export quotas and cultural situation and lifestyle. Türkiye scores the highest in terms of market size, GDP growth rate, access to raw materials and markets, technological infrastructure and innovation, transport networks, production sites, energy production, import and export quotas and business-friendly approaches.
Development of an HPLC method for the determination of fampridine (dalfampridine) in human plasma by fluorimetric derivatization and application to a prototype pharmacokinetic study
(Editions de l'Academie Republique Populaire, 2025) Ceylan, Burhan; Önal, Cem; Önal, Armağan
Fampridine (dalfampridine) is used to improve walking in people who have multiple sclerosis. In this study, a new, fast and sensitive HPLC method with fluorometric detection was developed for the determination of fampridine in human plasma and applied to a pharmacokinetic study. Fampridine was precolumn derivatized with 7-chloro-4-nitrobenzofurazan (NBD-Cl) and the fluorescent derivative was separated on a C18 (150 × 4.6 mm × 2.6 μm) analytical column at 30 ºC using a mobile phase composed of acetonitrile – 0.1% o-phosphoric acid in water (80:20, v/v) by isocratic elution with flow rate of 1.0 mL min–1 . The method was based on the measurement of the derivative using fluorescence detection (λex= 310 nm, λem = 365 nm). The retention time of fampridine is 4.10 ± 0.02 min. This currently developed method was validated according to EMA criteria by evaluating the specificity, linearity, precision, accuracy and robustness. The method was determined to be linear in a concentration range of 0.01–20 ng mL–1 with the correlation coefficient of 0.9996. LOD and LOQ were found to be 0.003 and 0.01 ng mL–1 , respectively. Intraday and interday RSD values were less than 2.45%. The plasma concentration-time profile and pharmacokinetic parameters such as AUC0–t, AUC0–∞, Cmax, tmax, t1/2, were calculated according to the assays. The presented method can certainly be used for bioequivalence and bioavailability investigations and routine analysis of the drug in plasma.
