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    Molecular mechanisms of heat shock proteins in distinct diseases
    (Scientific Scholar, 2023) Yürekli, Nazlıcan; Tutar, Merve; Niyazov, Laziz; Sağır, Fatma; Açıkalın Coşkun, Kübra; Al, Mervenur; Uçar Çifçi, Kezban; Abay, Cansu; Gök Yurttaş, Asiye; Okat, Zehra; Tutar, Yusuf; Asea, Alexzander A. A.; Kaur, Punit
    Heat shock proteins (HSPs) modulate the molecular mechanics of cells and cellular systems. Properly folded proteins are required for cellular processes and organisms use molecular mechanics to keep substrate proteins in their native state. Therefore, cellular compartments employ redundant isoforms of HSP to maintain substrate protein homeostasis and keep them functional. Hence, HSP folder function is critical for cell, HSPs are universally conserved. HSPs play essential roles in cellular signalling and in immune system besides their folder function. To this purpose, the roles of distinct HSP are described in this review to describe their molecular mechanisms in diseases.