Molecular mechanisms of heat shock proteins in distinct diseases
Yükleniyor...
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Scientific Scholar
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Heat shock proteins (HSPs) modulate the molecular mechanics of cells and cellular systems. Properly folded proteins are required for cellular processes and organisms use molecular mechanics to keep substrate proteins in their native state. Therefore, cellular compartments employ redundant isoforms of HSP to maintain substrate protein homeostasis and keep them functional. Hence, HSP folder function is critical for cell, HSPs are universally conserved. HSPs play essential roles in cellular signalling and in immune system besides their folder function. To this purpose, the roles of distinct HSP are described in this review to describe their molecular mechanisms in diseases.
Açıklama
Anahtar Kelimeler
Cancer, Heat Shock Proteins, HSP Inhibitors, Mutation, Neurodegenerative Diseases, Protein Folding
Kaynak
Heat Shock Proteins (HSP) in Translational Neuroscienc
WoS Q Değeri
Scopus Q Değeri
Cilt
27
Sayı
Künye
Yürekli, N., Tutar, M., Niyazov, L., Sağır, F., Açıkalın Coşkun, K., Al, M., Uçar Çifçi, K., Abay, C., Gök Yurttaş, A., Okat, Z., & Tutar, Y. (2023). Molecular mechanisms of heat shock proteins in distinct diseases. A. A. A. Asea, P. Kaur (Ed.), Heat Shock Proteins (HSP) in Translational Neuroscienc (pp. 38-56). New York: Scientific Scholar.
