In vitro evaluation of methyl methacrylate (MMA) release from different temporary denture base materials

dc.authorid0000-0002-7066-3032
dc.authorid0000-0002-3724-5656
dc.authorid0009-0007-6784-328X
dc.authorid0009-0005-5278-6767
dc.contributor.authorDilaverler Yardım, Esra Ayşe
dc.contributor.authorÖzer, Safa
dc.contributor.authorAtasoyu Akgün, Begüm
dc.contributor.authorÇakan, Umut
dc.date.accessioned2026-01-21T17:47:23Z
dc.date.available2026-01-21T17:47:23Z
dc.date.issued2025
dc.departmentFakülteler, Diş Hekimliği Fakültesi, Klinik Bilimler Bölümü, Protetik Diş Tedavisi Ana Bilim Dalı
dc.description.abstractINTRODUCTION: Residual methyl methacrylate (MMA) released from temporary denture base materials is of clinical concern due to its potential biological effects. Recently, light polymerized and 3D-printed denture base resins have emerged as alternatives to conventional cold-polymerized acrylics. This study aimed to compare the in vitro MMA release levels of three clinically relevant temporary denture base materials. MATERIALS AND METHODS: Three materials were tested: cold-polymerized acrylic resin, light-polymerized baseplate resin, and 3D-printed denture base resin. Ten samples were prepared for each group (n=10), standardized to 0.05 g per specimen. Samples were immersed in 2 mL and 5 mL of artificial saliva and incubated at 37°C. MMA release was quantified using high-performance liquid chromatography (HPLC) at 15 minutes, 30 minutes, 1 hour, and 24 hours. Data distribution was analyzed with the Shapiro-Wilk test; the effects of time, material, and saliva volume were assessed using two-way ANOVA and Tukey post-hoc tests (p<0.05). RESULTS: No MMA release was detected before 24 hours in the 3D-printed and light-polymerized groups. The cold polymerized acrylic group showed progressive MMA release starting from 15 minutes, with a significant increase over time (p<0.001). At 24 hours, it exhibited the highest MMA levels among all groups. A significant difference between 2 mL and 5 mL saliva volumes was observed only in the cold-cure group. The 3D-printed resin showed the most stable performance across all time points. CONCLUSION: Temporary denture base materials should be selected with consideration of residual monomer release. The results support the biocompatibility of 3D-printed resins for short-term clinical applications, especially when early MMA release and toxicity are of concern.
dc.identifier.citationDilaverler Yardım, E. A., Özer, S., Atasoyu Akgün, B., & Çakan, U. (2025). In vitro evaluation of methyl methacrylate (MMA) release from different temporary denture base materials. M. Özcan (Ed.), Abstracts from the 48th Annual Conference of the European Prosthodontic Association (EPA) 11th - 13th September 2025 Cappadocia, Turkey Oral Presentations, (p. 83), Cappadocia, Dennis Barber Journals.
dc.identifier.endpage83
dc.identifier.issn2396-8893
dc.identifier.issn0965-7452
dc.identifier.scopusqualityQ1
dc.identifier.startpage83
dc.identifier.urihttps://hdl.handle.net/20.500.13055/1257
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynak.otherESCI - Emerging Sources Citation Index
dc.institutionauthorDilaverler Yardım, Esra Ayşe
dc.institutionauthorAtasoyu Akgün, Begüm
dc.institutionauthorÇakan, Umut
dc.institutionauthorid0000-0002-7066-3032
dc.institutionauthorid0009-0007-6784-328X
dc.institutionauthorid0009-0005-5278-6767
dc.language.isoen
dc.publisherDennis Barber Journals
dc.relation.ispartofAbstracts from the 48th Annual Conference of the European Prosthodontic Association (EPA) 11th - 13th September 2025 Cappadocia, Turkey Oral Presentations
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subject3D-Printed Resin
dc.subjectMethyl Methacrylate
dc.subjectTemporary Denture Base
dc.subjectCold-Polymerized Acrylic
dc.subjectLight-Polymerized Baseplate
dc.subjectHPLC
dc.titleIn vitro evaluation of methyl methacrylate (MMA) release from different temporary denture base materials
dc.typeConference Object
dspace.entity.typePublication

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