In vitro evaluation of methyl methacrylate (MMA) release from different temporary denture base materials
| dc.authorid | 0000-0002-7066-3032 | |
| dc.authorid | 0000-0002-3724-5656 | |
| dc.authorid | 0009-0007-6784-328X | |
| dc.authorid | 0009-0005-5278-6767 | |
| dc.contributor.author | Dilaverler Yardım, Esra Ayşe | |
| dc.contributor.author | Özer, Safa | |
| dc.contributor.author | Atasoyu Akgün, Begüm | |
| dc.contributor.author | Çakan, Umut | |
| dc.date.accessioned | 2026-01-21T17:47:23Z | |
| dc.date.available | 2026-01-21T17:47:23Z | |
| dc.date.issued | 2025 | |
| dc.department | Fakülteler, Diş Hekimliği Fakültesi, Klinik Bilimler Bölümü, Protetik Diş Tedavisi Ana Bilim Dalı | |
| dc.description.abstract | INTRODUCTION: Residual methyl methacrylate (MMA) released from temporary denture base materials is of clinical concern due to its potential biological effects. Recently, light polymerized and 3D-printed denture base resins have emerged as alternatives to conventional cold-polymerized acrylics. This study aimed to compare the in vitro MMA release levels of three clinically relevant temporary denture base materials. MATERIALS AND METHODS: Three materials were tested: cold-polymerized acrylic resin, light-polymerized baseplate resin, and 3D-printed denture base resin. Ten samples were prepared for each group (n=10), standardized to 0.05 g per specimen. Samples were immersed in 2 mL and 5 mL of artificial saliva and incubated at 37°C. MMA release was quantified using high-performance liquid chromatography (HPLC) at 15 minutes, 30 minutes, 1 hour, and 24 hours. Data distribution was analyzed with the Shapiro-Wilk test; the effects of time, material, and saliva volume were assessed using two-way ANOVA and Tukey post-hoc tests (p<0.05). RESULTS: No MMA release was detected before 24 hours in the 3D-printed and light-polymerized groups. The cold polymerized acrylic group showed progressive MMA release starting from 15 minutes, with a significant increase over time (p<0.001). At 24 hours, it exhibited the highest MMA levels among all groups. A significant difference between 2 mL and 5 mL saliva volumes was observed only in the cold-cure group. The 3D-printed resin showed the most stable performance across all time points. CONCLUSION: Temporary denture base materials should be selected with consideration of residual monomer release. The results support the biocompatibility of 3D-printed resins for short-term clinical applications, especially when early MMA release and toxicity are of concern. | |
| dc.identifier.citation | Dilaverler Yardım, E. A., Özer, S., Atasoyu Akgün, B., & Çakan, U. (2025). In vitro evaluation of methyl methacrylate (MMA) release from different temporary denture base materials. M. Özcan (Ed.), Abstracts from the 48th Annual Conference of the European Prosthodontic Association (EPA) 11th - 13th September 2025 Cappadocia, Turkey Oral Presentations, (p. 83), Cappadocia, Dennis Barber Journals. | |
| dc.identifier.endpage | 83 | |
| dc.identifier.issn | 2396-8893 | |
| dc.identifier.issn | 0965-7452 | |
| dc.identifier.scopusquality | Q1 | |
| dc.identifier.startpage | 83 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.13055/1257 | |
| dc.identifier.wosquality | Q3 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.indekslendigikaynak.other | ESCI - Emerging Sources Citation Index | |
| dc.institutionauthor | Dilaverler Yardım, Esra Ayşe | |
| dc.institutionauthor | Atasoyu Akgün, Begüm | |
| dc.institutionauthor | Çakan, Umut | |
| dc.institutionauthorid | 0000-0002-7066-3032 | |
| dc.institutionauthorid | 0009-0007-6784-328X | |
| dc.institutionauthorid | 0009-0005-5278-6767 | |
| dc.language.iso | en | |
| dc.publisher | Dennis Barber Journals | |
| dc.relation.ispartof | Abstracts from the 48th Annual Conference of the European Prosthodontic Association (EPA) 11th - 13th September 2025 Cappadocia, Turkey Oral Presentations | |
| dc.relation.publicationcategory | Konferans Öğesi - Uluslararası - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | 3D-Printed Resin | |
| dc.subject | Methyl Methacrylate | |
| dc.subject | Temporary Denture Base | |
| dc.subject | Cold-Polymerized Acrylic | |
| dc.subject | Light-Polymerized Baseplate | |
| dc.subject | HPLC | |
| dc.title | In vitro evaluation of methyl methacrylate (MMA) release from different temporary denture base materials | |
| dc.type | Conference Object | |
| dspace.entity.type | Publication |












