Neural therapy in migraine: Clinical evidence for a holistic therapeutic approach - analysis of 464 cases

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dc.authorid0000-0002-9746-5220
dc.authorid0000-0002-9427-9529
dc.authorid0000-0003-0754-0854
dc.authorid0000-0002-3464-853X
dc.authorid0000-0002-9886-2017
dc.contributor.authorNazlıkul, Hüseyin
dc.contributor.authorUral Nazlıkul, Fatma Gülçin
dc.contributor.authorBilgin, Mehmet Dinçer
dc.contributor.authorAcarkan, Tijen
dc.contributor.authorÖzkan, Neslihan
dc.contributor.authorTamam, Yusuf
dc.date.accessioned2025-05-02T11:45:52Z
dc.date.available2025-05-02T11:45:52Z
dc.date.issued2025
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı
dc.description.abstractBackground: Migraine is one of the most common neurological disorders and significantly impairs quality of life. While conventional therapies may alleviate symptoms, they often fail to address the underlying causes. Neural therapy is a therapeutic approach in which local anesthetics such as procaine or lidocaine are not primarily used for analgesia but rather to modulate the autonomic nervous system, particularly its sympathetic branch. This method aims to restore functional balance and stabilize dysregulated networks through segmental and systemic reflex pathways, thereby supporting a holistic regulatory effect. Objective: This retrospective study aims to evaluate the effectiveness of neural therapy in 464 migraine patients using a holistic, regulatory medical approach. Methods: Patient history forms were analyzed for hormonal dysregulation, intestinal dysbiosis, temporomandibular dysfunction, C2 vertebral blockage, hydration status, and interference fields. Additionally, clinical treatment progressions were statistically assessed. Results: Over 91% of patients demonstrated clinical improvement, and 60% became symptom-free. The most frequently observed contributing factors were intestinal dysbiosis (89%), hormonal imbalance (71%), and temporomandibular/C2 dysfunctions (43% each). Conclusion: Neural therapy is an effective and regulatory therapeutic option for migraines, particularly in chronic, multifactorial cases. Its integration into a holistic treatment strategy may yield substantial clinical benefits.
dc.identifier.citationNazlıkul, H., Ural Nazlıkul, F. G., Bilgin, M. D., Acarkan, T., Özkan, N., & Tamam, Y. (2025). Neural therapy in migraine: Clinical evidence for a holistic therapeutic approach - analysis of 464 cases. International Clinical and Medical Case Report Journal, 4(4), pp. 1-27. https://doi.org/10.5281/zenodo.15262178
dc.identifier.doi10.5281/zenodo.15262178
dc.identifier.endpage23
dc.identifier.issn2832-5788
dc.identifier.issue4
dc.identifier.startpage1
dc.identifier.urihttps://doi.org/10.5281/zenodo.15262178
dc.identifier.urihttps://hdl.handle.net/20.500.13055/968
dc.identifier.volume4
dc.institutionauthorUral Nazlıkul, Fatma Gülçin
dc.institutionauthorid0000-0002-9427-9529
dc.language.isoen
dc.publisherSalient Visionary Publications LLC
dc.relation.ispartofInternational Clinical and Medical Case Report Journal
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectNeural Therapy
dc.subjectAutonomic Nervous System
dc.subjectLocal Anaesthetic (Procaine
dc.subjectLidocaine)
dc.subjectMigraine
dc.subjectRegulatory Approach
dc.titleNeural therapy in migraine: Clinical evidence for a holistic therapeutic approach - analysis of 464 cases
dc.typeArticle
dspace.entity.typePublication

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