Comparison of fetal cardiac structure in hypothyroid pregnant women receiving thyroid hormone replacement therapy and healthy controls

dc.authorid0000-0002-3654-9375en_US
dc.authorscopusid6507207850en_US
dc.contributor.authorAcar Şirinoğlu, Hicran
dc.contributor.authorUysal, Gülsüm
dc.contributor.authorAtakır, Kadir
dc.contributor.authorGenç, Simten
dc.contributor.authorMihmanlı, Veli
dc.date.accessioned2022-07-15T09:37:00Z
dc.date.available2022-07-15T09:37:00Z
dc.date.issued2022en_US
dc.departmentMeslek Yüksekokulları, Sağlık Hizmetleri Meslek Yüksekokulu, Tıbbi Görüntüleme Teknikleri Programıen_US
dc.description.abstractObjective: Thyroid hormone is required for normal fetal brain development, neuronal proliferation, migration and structural organization. We aimed to investigate fetal cardiac structure in fetuses of hypothyroid pregnant women receiving thyroid hormone replacement therapy and to compare it with normal pregnancies, including fetal outcome and delivery results. Methods: Singleton pregnant women whose ages were between 18–45 years and weeks of gestation were between 26–34 were included in the study. Their routine laboratory test reports, ultrasonographic measurements (fetal echo) and postnatal follow-up data were recorded. Patients were grouped according to the presence of diagnosis of hypothyroidism. The patients with hypothyroidism during pregnancy were included in Group 1 while healthy pregnancies with similar features were considered as controls and included in Group 2. All women with hypothyroidism were taking thyroid hormone replacement. All ultrasonographic and laboratory data measurements were collected from the system files and were compared between groups. Results: A total of 89 patients (41 hypothyroidism and 48 controls) were recruited to the study. Serum TSH levels of patients with hypothyroidism (Group 1) was significantly higher than the controls. In fetal cardiac examination, left ventricular (LV) and right ventricular (RV) wall thicknesses, and interventricular septum thicknesses at the end of systole and diastole were not statistically significant in both groups. Apgar scores, fetal gender and mean fetal birth weight were all similar between the groups. Conclusion: There is no myocardial structural difference in fetuses of pregnant women who were diagnosed with hypothyroidism and received thyroid hormone replacement theren_US
dc.identifier.citationAcar Şirinoğlu, H., Uysal, G., Atakır, K., Genç, S. & Mihmanlı, V. (2022). Comparison of fetal cardiac structure in hypothyroid pregnant women receiving thyroid hormone replacement therapy and healthy controls. Perinat Journal, 30(2), 179–184. 10.2399/prn.22.0302012en_US
dc.identifier.doi10.2399/prn.22.0302012en_US
dc.identifier.endpage184en_US
dc.identifier.issue2en_US
dc.identifier.startpage179en_US
dc.identifier.trdizinid536169
dc.identifier.urihttps://doi.org/10.2399/prn.22.0302012
dc.identifier.urihttps://hdl.handle.net/20.500.13055/236
dc.identifier.volume30en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorAtakır, Kadir
dc.language.isoenen_US
dc.publisherPerinatal Medicine Foundationen_US
dc.relation.ispartofPerinatal Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHypothyroidismen_US
dc.subjectFetal cardiac structureen_US
dc.subjectFetal Doppleren_US
dc.subjectEnd diastolic myocardial thicknessen_US
dc.subjectİnterventricular septumen_US
dc.titleComparison of fetal cardiac structure in hypothyroid pregnant women receiving thyroid hormone replacement therapy and healthy controlsen_US
dc.typeArticleen_US
dspace.entity.typePublication

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