İstanbul Sağlık ve Teknoloji Üniversitesi Kurumsal Akademik Arşivi
DSpace@İSTÜN, Üniversite mensupları tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Axillary mass following BCG vaccination: A rare case diagnosed as lipofibromatosis
(Turkiye Klinikleri Yayınevi, 2025) Özdil Yılmaz, İlkiz Özge
We present a case of a 7-month-old male infant who de veloped a progressive, painless left axillary mass 2 months after Bacil lus Calmette-Guérin (BCG) vaccination. Parents reported that the swelling has increased since the 4th month. Initial ultrasound revealed a 16×26×33 mm hyperechoic subcutaneous lesion with a central cystic area and minimal vascularity, suggesting a complicated lipoma. Due to continuous growth, the mass was surgically excised. Histopathological examination confirmed lipofibromatosis, a rare benign fibro-fatty tumor of infancy. Although axillary lymphadenitis is a common BCG com plication, persistent or atypical lesions should prompt further investi gation to rule out neoplasms. This case emphasizes the importance of considering rare soft tissue tumors like lipofibromatosis in the differ ential diagnosis of post-vaccination axillary masses.
Interoceptive alterations in post-stroke individuals: A comparative cross-sectional study
(SAGE Publications, 2025) Özgün, Mete; Akanyeti, Otar; Povina, F. Villagra; Dal Koyuncuoğlu, Beyza
Background and Aims: Interoception refers to the complex neuro physiological process of sensing, integrating, and modeling visceral and somatic inputs to generate real-time internal state monitoring which is crucial for homeostasis and adaptive cognitive-emotional responses. Within the framework of the allostatic interoception model, this internal sensing system not only reacts to current physiological demands but also predicts and prepares for anticipated needs. Discrepancies between pre dicted and actual interoceptive signals may cause allostatic overload, dis rupting neural signalling. So far, very few studies have investigated whether stroke impairs interoceptive networks and how these impairments are associated with cognitive and motor functions. This study, therefore, aimed to investigate interoceptive capacity in post-stoke individuals. Methods: Forty stroke patients with Mini-Mental Test scores of >25 were compared with forty healthy controls with similar age and sex dis tribution. Interoceptive dimensions were assessed through Heartbeat Detection Task for interoceptive accuracy, Interoceptive Sensory Scale for subjective sensitivity, and Toronto Alexithymia Scale for interoceptive awareness. Cognitive performance was evaluated with Trail-Making Test, while motor functioning was assessed with Fugl-Meyer Motor Scale. Results: demonstrated significantly reduced interoceptive accuracy, sen sitivity and elevated alexithymia scores in the stroke group compared to controls (p=0.018, p=0.043, p=0.038 respectively). No significant associa tion was observed between interoception and motor performance. However, interoceptive accuracy was positively correlated with cognitive function (r=0.248, p=0.037). Conclusions: Our findings indicate that stroke-related neurophysiologi cal alterations may deteriorate interoceptive function. Incorporating interoceptive assessments and targeted interventions into clinical reha bilitation may improve recovery outcomes. Further research is needed to clarify the contribution of interoceptive dysfunction to post-stroke cogni tive and emotional impairments (versus SNF) care was consistently associated with higher HT and decreased odds of mortality and readmission (Table 2). IRF (versus SNF) was associated with higher mean difference in HT percentage ranging from 21% to 23% in PS matched cohorts, IPTW analyses generated more modest estimates of mean HT difference (10.6%).
Classifying stroke recovery profiles based on living environment: A latent class analysis
(SAGE Publications, 2025) Özgün, Mete; Akanyeti, Otar; Povina, F. Villagra; Rahman, R.; Saybaşılı, Hale; Atalar, Deniz
Background and Aims: Post-stroke recovery is influenced by multiple factors including living environment. While skilled nursing homes may offer more comprehensive care, including physiotherapy, dietary support, and psychological counseling, many family caregivers remain concerned that such settings may lead to loneliness and a sense of abandonment in stroke survivors, which may negatively impact their recovery. This study investigates how different living environments influence functional and psychological outcomes. Methods: A total of 278 stroke survivors living either in their homes or nursing homes in Istanbul,Turkey were assessed. Patient outcomes were evaluated using Stroke Impact Scale, Stroke Specific Quality of Life Scale, Tampa Scale for Kinesiophobia, Geriatric Depression Scale, UCLA Loneliness Scale, and Tinetti Gait and Balance Test. Covariates included age, stroke years, education, medical history, treatments received and caregiver support. Results: Latent Class Analysis identified two distinct patient class, as shown in figure. Class 2 demonstrated significantly better outcomes char acterized by greater independence, improved quality of life, lower depres sion and loneliness scores, reduced kinesiophobia, lower fall risk, healthier exercise routines and sleep quality. While the overall sample included more individuals receiving home care, the class which exhibited better functional and psychological outcomes contained a higher proportion of nursing home residents. Results: Of the 382 patients, 78 were analyzed (31 stable/35 unstable plaques/12 acute occlusions). When analyzing early radiological changes, there was no significant difference between the three studied plaque types (p>0.05), while when monitoring early neurological changes (NIHSS), significant decrease in deficit was noted in stable (p=0.012) and unstable (p<0.001) plaques. A significant decrease in all groups was noted in late clinical changes (mRS, always p<0.001). However, no significant difference was found between studied plaque types and stroke severity (p>0.05) Conclusions: No significant association was found between carotid plaque morphology detected on CT and early/late stroke severity in carotid territory. Patients with stable plaques showed milder events and had better overall 3-month outcome.
Üniversite kütüphanelerinde yeni yaklaşımlar: Yapay zekâ kütüphaneciliği
(Bakı Dövlət Universiteti, 2025) Cihan, Hacı Bayram; Öztürk, Aytuğ
The aim of this study is to examine the changes in the duties and respon sibilities of librarians with the use of artificial intelligence in university libraries and to evaluate the effects of these changes on the librarianship profession. In this context, how artificial intelligence has transformed the librarianship profession, the opportunities and challenges librarians will face in adapting to new technologies, and the skills they need to acquire in this process will be examined. The study covers librarians working in university libraries and artificial intelligence technologies applied in libraries. The design of the research was created using the descriptive analysis method. The effects of artificial intelligence applications in libraries were detailed through the literature review method, academic articles, notifications, books, and websites. The data were examined using thematic analysis method and main themes and sub-themes were determined. The research findings show that generative artificial intelligence applications provide significant changes in data management, user services, and information access processes in libraries. These changes expand the duties of librarians and require them to acquire new skills. In particular, data analytics, machine learning, and digital archive management are among the basic skills of new-generation librarians. As a result, generative artificial intelligence technologies are creating new formations in the librarianship profession. It has been determined that librarians need to constantly renew themselves and adapt to technologies such as artificial intelligence to keep up with rapidly developing technologies. In this process, it has become a critical necessity for librarians to build their continuous learning and adaptation skills.
Flaxseed-based green electrolyte enabling high electrochemical stability for advanced zinc ion batteries
(Wiley, 2026) Arıkan, Yiğit Berke; Kömürcüoğlu, Gökçe; Adhami, Sadaf; Yaman Uzunoğlu, Gülşah; Yüksel, Recep
This study presents a green and sustainable electrolyte derived from flaxseeds (FS) aimed at enhancing the electrochemical stability of zinc-ion batteries (ZIBs), thereby reducing the occurrence of free water molecules and alleviating the hydrogen evolution reaction (HER) that contributes to the development of zinc (Zn) dendrites. The abundant hydroxyl groups present in polysaccharides and phenolic compounds within the flaxseeds coordinate with Zn2+, modifying the solvation sheath and reducing HER activity. Zn//Zn symmetric cells utilizing the FS-based electrolyte exhibited remarkably stable cycling for 3000 h at a current density of 1.0 mA cm−2 (1.0 mAh cm−2) and 2500 h at 2.0 mA cm−2 (2.0 mAh cm−2). Zn//V2O5 full cells delivered a discharge capacity of 233.8 mAh g−1 at 0.2 A g−1 and excellent rate capability across a wide current density range of 0.2–10 A g−1 . The ex situ SEM and XRD results confirmed uniform Zn deposition along the (002) plane without dendrite formation. This work demonstrates a biomass-derived, low-cost electrolyte formulation strategy that effectively stabilizes Zn interfaces, providing a green and efficient pathway for next-generation zinc-ion batteries.
