İstanbul Sağlık ve Teknoloji Üniversitesi Kurumsal Akademik Arşivi
DSpace@İSTÜN, Üniversite mensupları tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.

Güncel Gönderiler
Protetik diş hekimliğinde fotopolimer dental reçineler
(Gece Kitaplığı, 2025) Dilaverler Yardım, Esra Ayşe; Mert, Selen Elif
Protetik diş hekimliğinde kullanılan üretim yöntemleri, son yıllarda dijital teknolojilerin gelişimine paralel olarak önemli bir dönüşüm süre cinden geçmektedir. Geleneksel döküm, presleme ve frezeleme temelli üretim yöntemlerinin yerini, bilgisayar destekli tasarım ve üretim sistem leri (Computer-Aided Design/Computer-Aided Manufacturing – CAD/ CAM) ile birlikte eklemeli üretim teknolojileri (Additive Manufacturing – AM) almaya başlamıştır. Bu teknolojiler, üretim doğruluğunu ve işlem hızını artırarak materyal kullanımında verimlilik sağlamış, aynı zaman da kişiye özgü protetik restorasyonların üretilmesini mümkün kılmıştır.
Video-assisted learning on youtube in dentistry education: The impact of overdenture videos on dentistry students
(Dennis Barber Journals, 2025) Olkun, Abdullah Yaşar; Özkan, Yiğit Alp; Dilaverler Yardım, Esra Ayşe
OBJECTIVES: This study aimed to evaluate the effectiveness of video-assisted learning on the knowledge and perceptions of dental students regarding implant-supported overdentures, which represent a challenging but essential aspect of prosthodontic treatment. The increasing use of digital platforms for educational purposes motivated this research. MATERIALS-METHODS: A prospective pretest–posttest intervention study was conducted involving 4th- and 5th-year dental students at Istanbul Health and Technology University. Participants initially completed a 15-item multiple-choice test designed to assess their baseline theoretical knowledge of implant supported overdenture procedures. Students watched the selected educational video demonstrating key clinical steps, including implant positioning, abutment selection, impression-taking techniques, and prosthesis fitting. After the video session, students completed the same knowledge test to evaluate knowledge gain, as well as a 10-item Likert-scale survey to assess their perceptions about the video’s clarity, educational value, engagement, and motivational impact. Data were statistically analyzed using paired t-tests for knowledge score comparisons and descriptive statistics for survey results.Students complete the survey via Google Forms. RESULTS: Analysis revealed a statistically significant increase in post-intervention test scores, indicating an improvement in students’ understanding of overdenture concepts and clinical procedures. Survey responses reflected positive student attitudes toward video-assisted learning, highlighting increased clarity, engagement, and confidence in managing implant-supported overdentures. Most students expressed a preference for integrating similar video modules into their formal prosthodontic education. CONCLUSION: Video-assisted learning through widely accessible platforms such as YouTube serves as an effective supplementary educational tool in dental training. It enhances both theoretical knowledge and practical confidence in complex prosthodontic procedures like implant-supported overdentures. Incorporating such multimedia resources into dental curricula is strongly recommended to enrich student learning experiences and outcomes.
In vitro evaluation of methyl methacrylate (MMA) release from different temporary denture base materials
(Dennis Barber Journals, 2025) Dilaverler Yardım, Esra Ayşe; Özer, Safa; Atasoyu Akgün, Begüm; Çakan, Umut
INTRODUCTION: Residual methyl methacrylate (MMA) released from temporary denture base materials is of clinical concern due to its potential biological effects. Recently, light polymerized and 3D-printed denture base resins have emerged as alternatives to conventional cold-polymerized acrylics. This study aimed to compare the in vitro MMA release levels of three clinically relevant temporary denture base materials. MATERIALS AND METHODS: Three materials were tested: cold-polymerized acrylic resin, light-polymerized baseplate resin, and 3D-printed denture base resin. Ten samples were prepared for each group (n=10), standardized to 0.05 g per specimen. Samples were immersed in 2 mL and 5 mL of artificial saliva and incubated at 37°C. MMA release was quantified using high-performance liquid chromatography (HPLC) at 15 minutes, 30 minutes, 1 hour, and 24 hours. Data distribution was analyzed with the Shapiro-Wilk test; the effects of time, material, and saliva volume were assessed using two-way ANOVA and Tukey post-hoc tests (p<0.05). RESULTS: No MMA release was detected before 24 hours in the 3D-printed and light-polymerized groups. The cold polymerized acrylic group showed progressive MMA release starting from 15 minutes, with a significant increase over time (p<0.001). At 24 hours, it exhibited the highest MMA levels among all groups. A significant difference between 2 mL and 5 mL saliva volumes was observed only in the cold-cure group. The 3D-printed resin showed the most stable performance across all time points. CONCLUSION: Temporary denture base materials should be selected with consideration of residual monomer release. The results support the biocompatibility of 3D-printed resins for short-term clinical applications, especially when early MMA release and toxicity are of concern.
The effect of commonly used polishing protocols on the color stability of 3D- printed temporary crowns
(Dennis Barber Journals, 2025) Yazar Özdemir, Nedime Zeynep; Dilaverler Yardım, Esra Ayşe
OBJECTIVE: Color stability is a crucial parameter for maintaining the long-term esthetic success of temporary restorations. This study aimed to evaluate the effects of different clinical polishing protocols applied to three-dimensional (3D) printed temporary resin crowns on their color stability. MATERIALS-METHODS: Fifty standardized specimens (12×12×2 mm) were prepared using a 3D printing resin material (PowerResins, Temp Resin, A2, Turkiye) and randomly divided into five groups (n=10) as G1: Control (no polishing), G2: Mechanical polishing (DCPT 14 RA SET), G3: Silicon dioxide containing polishing paste (Promida Prophy P), G4: Mechanical + silicon dioxide paste, G5: Diamond particle-containing polishing paste (Intensiv Unigloss). Initial color measurements were performed using a digital spectrophotometer (Vita Easyshade V). TSpecimens were exposed to a daily coffee cycle for 15 days. Color differences were calculated using the CIEDE2000 (ΔE00) formula, and the data were analyzed by one way analysis of variance (ANOVA). Tukey’s post-hoc test was applied for multiple comparisons (p < 0.05). RESULTS: No significant differences were observed between the groups before the coffee staining cycle (p > 0.05). After staining, intergroup differences were statistically significant (p < 0.05). The lowest ΔE00 values were recorded in G5 (diamond particle- containing polish). G3 and G4 exhibited moderate color changes, comparable to the control group (G1). The highest color change was observed in G2 (mechanical polishing only), with ΔE00 values exceeding the clinically perceptible threshold (ΔE00 ≥ 0.8). CONCLUSION: The diamond particle-containing polishing paste provided the best color stability both statistically and clinically. The polishing protocol plays a decisive role in the color stability of 3D-printed temporary crowns. The use of diamond-containing polishing systems is recommended, particularly in esthetic zone restorations.
What is new in the 2025 APASL guidelines for metabolic dysfunction-associated fatty liver disease?
(AME Publishing Company, 2026) Pan, Ziyan; Örmeci, Necati; Chen, Jinjun; Ghazinian, Hasmik; Payawal, Diana; Eslam, Mohammed
As the global epidemics of obesity and type 2 diabetes mellitus (T2DM) continue to rise, metabolic dysfunction associated fatty liver disease (MAFLD) has become the most common chronic liver disease globally. The Asia-Pacific region is particularly affected, accounting for a significant majority of global liver-related deaths (1). To address this, the Asian Pacific Association for the Study of the Liver (APASL) has released updated clinical practice guidelines in 2025 (2). This article is a commentary focusing on the key changes and new recommendations within those guidelines, which were published in Hepatology International (2). Recognizing the limitations of the exclusionary diagnostic criteria for non-alcoholic fatty liver disease (NAFLD) and emphasizing the key role of metabolic dysfunction in disease pathogenesis, the introduction of the MAFLD definition in 2020 was a milestone in disease research and clinical practice (3-5). This shift reflects a significant evolution in our understanding of the disease, moving away from a diagnosis of exclusion towards one of inclusion based on metabolic dysfunction, recognizing the central role of metabolic factors and introducing the key concept of dual etiology, including alcohol consumption or coexisting liver diseases (6). Over the past 5 years, there have been significant advancements in understanding the disease, culminating in new knowledge, the first approved treatment, and the beginning of a new era of artificial intelligence (AI) with potential promise for hepatology. These changes stimulate the need for an updated document of the APASL guidelines for the diagnosis and management of MAFLD, which was recently released in 2025 (2). This updated guideline provides a comprehensive framework for addressing the growing burden of MAFLD in the Asia-Pacific region. This commentary aims to highlight the key aspects in this landmark document and touch on the main changes from the 2020 version (7).
























