İstanbul Sağlık ve Teknoloji Üniversitesi Kurumsal Akademik Arşivi
DSpace@İSTÜN, Üniversite mensupları tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Enhancing home-based exercise therapy with telerehabilitation in mild adolescent idiopathic scoliosis: A randomized controlled trial
(MDPI Publishing, 2025) Takinacı, Zuhal Didem; Çelik, Meltem; Yıldız, Şeyda; Talmaç, Mehmet Ali; Dut, Raziye
Background and Objectives: Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity that affects postural alignment, function, and quality of life. Telere habilitation has emerged as a promising approach to enhance accessibility and conti nuity of exercise-based treatment in AIS. This study aimed to compare the effects of telerehabilitation-supported home exercise programs with standard home exercises on posture, pain, body image, and quality of life in adolescents with mild AIS. Materials and Methods: Forty adolescents aged 10–18 years with mild AIS (Cobb angle 10–25◦ , Risser 0–3) were randomly assigned to two groups: study (n = 20) and control (n = 20). Both groups performed an 8-week home-based exercise program. The study group addition ally received weekly online supervision by a physiotherapist. Outcomes included pain severity (VAS), posture (New York Posture Assessment Scale), body image (Walter Reed Visual Assessment Scale), and quality of life (SRS-22 questionnaire). Statistical analyses were performed using non-parametric tests, with a significance level of p < 0.05. Results: Twenty-nine participants completed the study (15 in the study group, 14 in the control group). Significant improvements were observed in the study group in SRS-22 total, pain, and function subscores, as well as posture scores (p < 0.05). In the control group, only the satisfaction subscore improved significantly (p < 0.05). No significant changes were detected in body image (WRVAS) in either group. Between-group comparisons showed greater overall clinical gains in the study group despite similar exercise adherence rates. Conclusions: Supervised telerehabilitation enhances the effectiveness of home-based exer cise programs in adolescents with mild AIS by improving postural alignment, reducing pain, and increasing functional capacity and quality of life. Telerehabilitation represents an accessible and efficient complementary strategy for managing AIS when in-person supervision is limited.
Green light and intermittent lighting modulate testicular gonadotropin inhibitory hormone without central or morphological effects in broiler chickens
(Islamic Azad University, 2025) Aykoç Göçer, Miray; Akın, S. G.; Özel Armutoğlu, Emine; Koç Yıldırım, Ece
Environmental factors, especially light duration and wavelength (colour), affect reproductive physiology in broilers. In birds, light is perceived especially by extraretinal photoreceptors in the brain, including the hy pothalamus, which regulates reproductive function. Gonadotropin-inhibitory hormone (GnIH), expressed in both the hypothalamus and gonads, suppresses gonadotropin release and modulates reproductive activity. Its expression is influenced by photoperiod and light colour. Rooster fertility is economically important, as one male can inseminate many females. This study investigated how green light and intermittent lighting affect GnIH levels and testicular development in prepubertal broiler males. 288 one-day-old male commer cial broilers (Ross-308) were divided into four groups (n=12) and exposed to: Group I, 18 hours light - 6 hours dark (18L:6D) with white light; Group II, 18L:6D with green light; Group III, 17L:3D:1L:3D with white light; and Group IV, 17L:3D:1L:3D with green light. The study was conducted in four identical ex perimental rooms, each consisting of six pens (replicates). Two male broilers were randomly selected from each pen. A total of 48 chickens, 2 males from each pen (replicate group), were randomly selected for analysis. After 42 days under standard conditions, GnIH levels were measured in the hypothalamus and testes via ELISA. Testicular development was assessed histologically by evaluating seminiferous tubule diameter and epithelial height. Results showed that intermittent lighting and green light significantly in creased testicular GnIH levels but had no effect on hypothalamic GnIH. The most pronounced increase in testicular GnIH was observed in Group IV, which received both intermittent lighting and green light. No significant differences were observed in testicular morphology. These findings suggest that intermittent lighting and green light may selectively influence gonadal GnIH levels without affecting central GnIH or morphology, offering insight into how lighting strategies may be optimized in poultry production.
Axillary mass following BCG vaccination: A rare case diagnosed as lipofibromatosis
(Turkiye Klinikleri Yayınevi, 2025) Özdil Yılmaz, İlkiz Özge
We present a case of a 7-month-old male infant who de veloped a progressive, painless left axillary mass 2 months after Bacil lus Calmette-Guérin (BCG) vaccination. Parents reported that the swelling has increased since the 4th month. Initial ultrasound revealed a 16×26×33 mm hyperechoic subcutaneous lesion with a central cystic area and minimal vascularity, suggesting a complicated lipoma. Due to continuous growth, the mass was surgically excised. Histopathological examination confirmed lipofibromatosis, a rare benign fibro-fatty tumor of infancy. Although axillary lymphadenitis is a common BCG com plication, persistent or atypical lesions should prompt further investi gation to rule out neoplasms. This case emphasizes the importance of considering rare soft tissue tumors like lipofibromatosis in the differ ential diagnosis of post-vaccination axillary masses.
Interoceptive alterations in post-stroke individuals: A comparative cross-sectional study
(SAGE Publications, 2025) Özgün, Mete; Akanyeti, Otar; Povina, F. Villagra; Dal Koyuncuoğlu, Beyza
Background and Aims: Interoception refers to the complex neuro physiological process of sensing, integrating, and modeling visceral and somatic inputs to generate real-time internal state monitoring which is crucial for homeostasis and adaptive cognitive-emotional responses. Within the framework of the allostatic interoception model, this internal sensing system not only reacts to current physiological demands but also predicts and prepares for anticipated needs. Discrepancies between pre dicted and actual interoceptive signals may cause allostatic overload, dis rupting neural signalling. So far, very few studies have investigated whether stroke impairs interoceptive networks and how these impairments are associated with cognitive and motor functions. This study, therefore, aimed to investigate interoceptive capacity in post-stoke individuals. Methods: Forty stroke patients with Mini-Mental Test scores of >25 were compared with forty healthy controls with similar age and sex dis tribution. Interoceptive dimensions were assessed through Heartbeat Detection Task for interoceptive accuracy, Interoceptive Sensory Scale for subjective sensitivity, and Toronto Alexithymia Scale for interoceptive awareness. Cognitive performance was evaluated with Trail-Making Test, while motor functioning was assessed with Fugl-Meyer Motor Scale. Results: demonstrated significantly reduced interoceptive accuracy, sen sitivity and elevated alexithymia scores in the stroke group compared to controls (p=0.018, p=0.043, p=0.038 respectively). No significant associa tion was observed between interoception and motor performance. However, interoceptive accuracy was positively correlated with cognitive function (r=0.248, p=0.037). Conclusions: Our findings indicate that stroke-related neurophysiologi cal alterations may deteriorate interoceptive function. Incorporating interoceptive assessments and targeted interventions into clinical reha bilitation may improve recovery outcomes. Further research is needed to clarify the contribution of interoceptive dysfunction to post-stroke cogni tive and emotional impairments (versus SNF) care was consistently associated with higher HT and decreased odds of mortality and readmission (Table 2). IRF (versus SNF) was associated with higher mean difference in HT percentage ranging from 21% to 23% in PS matched cohorts, IPTW analyses generated more modest estimates of mean HT difference (10.6%).
Classifying stroke recovery profiles based on living environment: A latent class analysis
(SAGE Publications, 2025) Özgün, Mete; Akanyeti, Otar; Povina, F. Villagra; Rahman, R.; Saybaşılı, Hale; Atalar, Deniz
Background and Aims: Post-stroke recovery is influenced by multiple factors including living environment. While skilled nursing homes may offer more comprehensive care, including physiotherapy, dietary support, and psychological counseling, many family caregivers remain concerned that such settings may lead to loneliness and a sense of abandonment in stroke survivors, which may negatively impact their recovery. This study investigates how different living environments influence functional and psychological outcomes. Methods: A total of 278 stroke survivors living either in their homes or nursing homes in Istanbul,Turkey were assessed. Patient outcomes were evaluated using Stroke Impact Scale, Stroke Specific Quality of Life Scale, Tampa Scale for Kinesiophobia, Geriatric Depression Scale, UCLA Loneliness Scale, and Tinetti Gait and Balance Test. Covariates included age, stroke years, education, medical history, treatments received and caregiver support. Results: Latent Class Analysis identified two distinct patient class, as shown in figure. Class 2 demonstrated significantly better outcomes char acterized by greater independence, improved quality of life, lower depres sion and loneliness scores, reduced kinesiophobia, lower fall risk, healthier exercise routines and sleep quality. While the overall sample included more individuals receiving home care, the class which exhibited better functional and psychological outcomes contained a higher proportion of nursing home residents. Results: Of the 382 patients, 78 were analyzed (31 stable/35 unstable plaques/12 acute occlusions). When analyzing early radiological changes, there was no significant difference between the three studied plaque types (p>0.05), while when monitoring early neurological changes (NIHSS), significant decrease in deficit was noted in stable (p=0.012) and unstable (p<0.001) plaques. A significant decrease in all groups was noted in late clinical changes (mRS, always p<0.001). However, no significant difference was found between studied plaque types and stroke severity (p>0.05) Conclusions: No significant association was found between carotid plaque morphology detected on CT and early/late stroke severity in carotid territory. Patients with stable plaques showed milder events and had better overall 3-month outcome.
