İstanbul Sağlık ve Teknoloji Üniversitesi Kurumsal Akademik Arşivi
DSpace@İSTÜN, Üniversite mensupları tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Human papillomavirus vaccines in obstetrics and pediatrics: A comprehensive review
(Medihealth Academy, 2025) Gürbüz, Tuğba; Özdil Yılmaz, İlkiz Özge
This review highlights the epidemiological significance, immunological function, and economic feasibility of Human papillomavirus (HPV) immunization, emphasizing both its benefits and challenges. Addressing vaccine hesitancy, ensuring equitable access, and expanding vaccination coverage for both genders are crucial to maximizing public health benefits. HPV is a highly prevalent infection with significant implications for global public health, particularly in obstetric and pediatric populations. Persistent infection with high-risk HPV genotypes, such as HPV-16 and HPV-18, is a leading cause of cervical cancer, a major contributor to cancer-related mortality worldwide. Beyond cervical malignancies, HPV is etiologically linked to anal, vulvar, vaginal, penile, and oropharyngeal carcinomas. Additionally, it is responsible for benign but distressing conditions such as genital warts, imposing substantial psychosocial and economic burdens. Prophylactic HPV vaccines have significantly improved the prevention of HPV-associated diseases. The currently available bivalent, quadrivalent, and nonavalent vaccines target high-risk oncogenic HPV types and provide near-complete protection against vaccine-included genotypes. These vaccines function by eliciting a robust immune response, effectively neutralizing HPV before it establishes an infection. However, despite their well-documented benefits, challenges such as vaccine hesitancy, misinformation, economic barriers, and global disparities in vaccine access persist. This review provides a comprehensive analysis of HPV immunization within obstetrics and pediatrics, emphasizing its epidemiological impact, immunological mechanisms, efficacy, safety, and implementation strategies. Furthermore, we explore existing barriers to vaccine uptake, disparities in global access, and potential future advancements, including next-generation vaccines and therapeutic interventions. Addressing these challenges through targeted public health initiatives, healthcare provider education, and equitable vaccine distribution strategies is essential to maximizing the public health impact of HPV immunization and reducing the global burden of diseases associated with HPV
Investigating impostor syndrome among postgraduate anatomy students
(Galenos Publishing House, 2025) Ok, Fatma; Karip, Burak; Nteli Chatzioglou, Gkionoul; Temizsoy Korkmaz, Fulya; Yiğit, Mehmet
Background: Impostor syndrome (IS) is marked by persistent self-doubt and the fear of being perceived as a fraud, even in the presence of clear accomplishments, and it notably affects high-achieving individuals. This study examined IS prevalence and associated factors among postgraduate anatomy students in Türkiye. Materials and Methods: Using the Clance Impostor Phenomenon Scale, 79 participants were surveyed to assess IS levels alongside demographic and psychiatric variables. Results: The results revealed that 39.2% of participants exhibited frequent impostor feelings (FIF) or intense impostor experiences (IIE). Notably, individuals with psychiatric conditions had significantly higher IS levels, with 64.7% classified in the FIF category and 17.6% in IIE, compared to those without psychiatric issues, who predominantly fell into lower IS categories (p<0.05). No statistically significant associations were observed between IS and demographic variables, including gender, marital status, or education level. However, individuals with no income were overrepresented in the IIE category, aligning with findings from studies suggesting a link between socioeconomic status and heightened IS levels. Conclusion: This study underscores the prevalence of IS in postgraduate students within a demanding academic discipline and highlights its association with psychiatric conditions. Increasing awareness of IS, particularly in high-stress, perfectionist professions such as academia, is critical. Such efforts can improve recognition, provide targeted interventions, and mitigate IS’s impact on individual well-being and professional performance.
Economic determinants of nonperforming loans in Turkey: Quantile ARDL results
(Istanbul University Press, 2025) Atılgan Sarıdoğan, Ayşe; Küçükgergerli, Nabi; Yaman, Adem
In the banking sector, problems in repaying customers’ credits can increase credit risk and fragility. Therefore, it is of great importance for banks to monitor the status of non-performing loans (NPLs) closely. This study analyzes the macroeconomic factors affecting NLPs in the Turkish banking sector. It used ARDL and QARDL approaches and data for 2011M5-2024M9 in the study. According to the long-run estimation results of the ARDL model, inflation and industrial production affect the NLPs in the opposite direction. In contrast, unemployment, the exchange rate, and interest rates affect it in the same direction. The estimation results are consistent with economic theory and the literature. The QARDL estimation results show that lnCPI (τ=0.2 to τ=0.8) has negative and significant coefficients in most quantiles (τ). The coefficients for lnPMI are generally negative and statistically insignificant. The lnUNE variable has positive and significant coefficients at most levels τ (τ=0.1 to τ=0.8). The estimation results for lnEXC show that the overall effect of the variable on NPL is positive and significant. The coefficients of interest rates are generally positive and significant. For the increase in the NLPs to remain at an acceptable threshold level for the banking sector and the Turkish economy, it is critical that the credit risk assessment system at the banking level works effectively and efficiently on the one hand and that macroeconomic indicators in the Turkish economy are supportive of the credit repayment conditions of economic agents on the other.
Examination of anatomical features of zygomaticofacial foramen in children: A 3d reconstruction study
(Springer Nature Link, 2025) Ay, Tuğba; Kervancıoğlu, Piraye; Adanır, Saliha Seda; Yalçın, Eda Didem
Background Considering the implications of surgical fixation techniques such as plating, screwing, or wiring in pediatric zygomatic fractures, a detailed understanding of the zygomaticofacial foramen (ZFF) anatomy in children may help reduce intraoperative complications particularly injury to the zygomaticofacial nerve, which passes through the ZFF. Objective The aim of the present study is to examine the morphometric and morphological features of the ZFF in the pediatric population. Methods Before the study commenced, approval was obtained from Gaziantep University Clinical Research Ethics Committee (Approval number: 2024/177). Cone-beam computed tomography (CBCT) images of 119 patients who applied to Gaziantep University Faculty of Dentistry, Department of Oral and Maxillofacial Radiology for any reason were retrospectively examined with Radiant DICOM Viewer program. The presence, number, localization and distances to certain anatomical points of ZFF were measured. The ZFF was classified based on the number of foramina. To determine the localization of the foramen, the lateral surface of zygomatic bone was divided into four quadrants using two reference lines. These quadrants were designated as a, b, c, and d in a clockwise direction from the inferomedial to the superomedial region. Statistical analyses were performed with SPSS 24.0 package program and p < 0.05 was considered statistically significant. Results A total of 119 children (male: 65, female: 54; mean age: 13.14 ± 3.24) CBCT images (238 sides) were examined. In the classification based on the number of foramina, the absence of any foramen was defined as Type 0 (106, 44.5%); the presence of one, two, and three foramina was classified as Type I (91, 38.2%), Type II (35, 14.7%), and Type III (6, 2.5%), respectively. The mean distance between ZFF-orbit and ZFF-temporozygomatic suture was greater in male than in female (p = 0.006, p = 0.009, respectively). The mean distance between ZFF-frontozygomatic suture was greater in female (p = 0.032). The distances between ZFF-zygomaticomaxillary suture and lowest point of zygomatic bone were significantly different between age groups (p = 0.026, p = 0.004, respectively). Conclusion The findings of the present study indicate that the zygomaticofacial foramen (ZFF) is most frequently located in region c and rarely in region b. Based on this observation, region b may represent a safer zone for surgical interventions in this area. The findings of the present study may help to minimize complications in surgeries and invasive procedures involving the zygoma region in children.
Impact of bruxism on the mandibular angle and condylar structures: A panoramic radiographic assessment
(Springer Nature Link, 2025) Artaş, Aslıhan; Aslan Öztürk, Elif Meltem
Objectives The aim of this study is to comparatively evaluate morphologic changes in the mandibular angle and condylar region, assess the mandibular cortical index (MCI), and analyze the relationships between these parameters in bruxers and non-bruxers using panoramic radiographs. Methods A total of 182 patients (364 mandibular condyle and angle), 91 bruxers and 91 non-bruxers (controls), aged between 18 and 35, were participated in this study. Three hundred sixty four mandibular angles were classifed as G0, G1, G2, G3 in terms of bone apposition and direction change. In addition, osseous changes in the mandibular condyle were determined and the endoestal edge of the basal cortex was evaluated according to the MCI classifcation. Parameters were analyzed using the Pearson’s Chi-Square test and Fisher's Exact test. A p value<0.05 was considered signifcant. Result MCI class C1, G0 class, and normal condyle type were found to be signifcantly more common in the non-bruxist group than in the bruxist group (p<0.001, p=0.025, p=0.006, respectively). It was determined that deformity and MCI-C2 class were more common in the bruxist group (p=0.006, p<0.001). Morphologic changes in the endosteal margin of the cortex and in the condylar region were observed more frequently in bruxist individuals. Conclusion For a general overview of the probable presence of bruxism, osseous changes in the mandibular condyle, and MCI can be used as auxiliary diagnostic markers.
