Molecular docking analysis of PVDF membrane against human Erα, EGFR, CDK2, mTOR, and HSP90 proteins

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dc.authorid0000-0003-3555-0267en_US
dc.authorid0000-0003-1375-7443en_US
dc.contributor.authorAta, Fatma Kübra
dc.contributor.authorÖzevci, Gülçin
dc.date.accessioned2023-01-20T08:49:33Z
dc.date.available2023-01-20T08:49:33Z
dc.date.issued2022en_US
dc.departmentMeslek Yüksekokulları, Sağlık Hizmetleri Meslek Yüksekokulu, Tıbbi Görüntüleme Teknikleri Programıen_US
dc.departmentMeslek Yüksekokulları, Sağlık Hizmetleri Meslek Yüksekokulu, Tıbbi Laboratuvar Teknikleri Programıen_US
dc.description.abstractPorous membranes are used in biological and chemical systems and industrial applications. Polyvinylidene fluoride film (PVDF) membrane is a commercial membrane used in drug delivery, protein immobilization, food industry, tissue engineering, and medical devices. Because of providing a large surface area in this study PVDF membrane is used. Molecular docking is a molecular modeling simulation software especially used to determine protein-ligand interactions. The aim of the study is to determine the interaction of hydrophobic PVDF membranes on Erα, EGFR, CDK2, mTOR, and HSP90 proteins by docking method and to examine its potential as a possible drug carrier. The three-dimensional structure of the receptors has been acquired from the RCSB protein data bank and is docked with 3D PubChem of PVDF using AutoDock 1.5.6 software. The results have shown that the PVDF membrane had the best docking score for mTOR between the investigated proteins.en_US
dc.identifier.citationAta, F. K. & Özevci, G. (2022). Molecular docking analysis of PVDF membrane against human Erα, EGFR, CDK2, mTOR, and HSP90 proteins. 10th International Symposium on Innovative Technologies in Engineering and Science içinde (pp. 530-536). Bursa: Academic Perspective Procedia. https://doi.org/10.33793/acperpro.05.03.14021en_US
dc.identifier.doi10.33793/acperpro.05.03.14021en_US
dc.identifier.endpage536en_US
dc.identifier.issn2667-5862
dc.identifier.issue3en_US
dc.identifier.startpage530en_US
dc.identifier.urihttps://doi.org/10.33793/acperpro.05.03.14021
dc.identifier.urihttps://hdl.handle.net/20.500.13055/376
dc.identifier.volume5en_US
dc.language.isoenen_US
dc.publisherAcademic Perspective Procediaen_US
dc.relation.ispartof10th International Symposium on Innovative Technologies in Engineering and Scienceen_US
dc.relation.publicationcategoryKonferans Öğesi - Ulusal - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPVDF Membraneen_US
dc.subjectMtoren_US
dc.subjectDrug Carrieren_US
dc.subjectMolecular Dockingen_US
dc.titleMolecular docking analysis of PVDF membrane against human Erα, EGFR, CDK2, mTOR, and HSP90 proteinsen_US
dc.typeConference Objecten_US
dspace.entity.typePublication

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