Histological staining technics for identifying various structures for histological assessment of bone and cartilage healing

dc.authorid0000-0003-4470-7465
dc.contributor.authorDikmen, Tayfun
dc.date.accessioned2025-01-28T17:42:58Z
dc.date.available2025-01-28T17:42:58Z
dc.date.issued2023
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü
dc.description.abstractBone and cartilage regeneration are challenging topics which the scientists are constantly looking for new approaches to eliminate current limitations of the traditional therapeutic methods which are being used. Cellular therapy and use of biomaterials for that purpose is providing encouraging results, especially in cases like osteoarthritis and bone healing. In such studies, the histological assessment of the healing of corresponding tissues are vital to determine to see if the developed method is indeed resulted with positive outcomes or not. Each tissue has some different distinctive structures that must be investigated during the healing process. There are several histological staining technics being used for the evaluation of the healing of bone and cartilage tissues by identifying the structures of interest. Among them, hematoxylin eosin staining comes forward as the most applied technic. However, it is not suitable to identify each and every important histological structure, and some specific staining technics are necessary to identify such structures like new bone formation areas, mineralized bone areas, glycosaminoglycan aggregates, collagen fiber formation, etc; regarding the aim of the research. In this study, bone and articular cartilage samples were taken and stained with Alcian blue staining, Picro-sirius red staining, Masson-Goldner’s trichrome staining, Movat’s pentachrome staining, von Kossa staining technics to identify different structures in bone and cartilage. The outcomes might help researchers to determine the appropriate staining technics to be used in their studies to fully demonstrate their findings.
dc.identifier.citationDikmen, T. (2023). Histological staining technics for identifying various structures for histological assessment of bone and cartilage healing. International congress on biological and health sciences, pp. 105. ICBH
dc.identifier.endpage105
dc.identifier.isbn9786057136848
dc.identifier.startpage105
dc.identifier.urihttps://hdl.handle.net/20.500.13055/907
dc.institutionauthorDikmen, Tayfun
dc.institutionauthorid0000-0003-4470-7465
dc.language.isoen
dc.publisherICBH
dc.relation.ispartofInternational Congress on Biological and Health Sciences
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHistological Assessment
dc.subjectHistological Staining
dc.subjectBone Healing
dc.subjectCartilage Healing
dc.titleHistological staining technics for identifying various structures for histological assessment of bone and cartilage healing
dc.typeConference Object
dspace.entity.typePublication

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