Assessment of carotid artery intima-media thickness and lipid profile in term neonates born to smoking mothers

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dc.authorscopusid57682332400en_US
dc.contributor.authorTuran, Hande
dc.contributor.authorMeşe, Timur
dc.contributor.authorDoksöz, Önder
dc.contributor.authorTuran, Volkan
dc.date.accessioned2022-01-19T13:38:15Z
dc.date.available2022-01-19T13:38:15Z
dc.date.issued2021en_US
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalıen_US
dc.description.abstractBackground: It is well-known that cigarette smoke contains chemical substances, including nicotine and carbon monoxide, which can have harmful effects on cardiovascular function. Objectives: This study aimed to investigate and compare lipid levels and carotid artery intima-media thickness (CAIMT) among neonates born to smoking and nonsmoking mothers. Methods: This study was conducted on 40 term neonates (over 37 weeks of gestation) within the age range of 0 - 30 days born to smoking mothers (study group) and 34 term neonates born to nonsmoking mothers (control group). Both groups were assessed prospectively for triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and CAIMT. Results: There was no difference in the mean age of mothers between control and study groups (29.0 4.5 vs. 29.3 5.7 years; P = 0.31). The CAIMT was observed as similar between the groups (0.35 0.05 vs. 0.36 0.05 mm in control and study groups, respectively; P = 0.665). Although HDL-C levels were significantly lower in the study group (48.5 16.2 vs. 39.1 17.8 mg/dL; P = 0.021), no difference was observed in LDL-C, TC, and TG levels between the two groups. Conclusions: Based on the results, there were no differences in CAIMT and lipid profile other than low HDL levels between term neonates born to smoking mothers and neonates born to nonsmoking mothers. Atherosclerosis is a disease in which numerous factors play a role in the formation beginning in the fetal period and emerging with clinical findings in advanced age; therefore, it is required to perform further studies with longer follow-up and larger sample size to confirm the present study findings.en_US
dc.identifier.citationTuran, H., Meşe, T., Doksöz, O., & Turan, V. (2021). Assessment of Carotid Artery Intima-Media Thickness and Lipid Profile in Term Neonates Born to Smoking Mothers. Iranian Journal of Pediatrics, 31(6), pp. 1-6. https://doi.org/10.5812/ijp.112313 ‌en_US
dc.identifier.doi10.5812/ijp.112313en_US
dc.identifier.endpage6en_US
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85129964337en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://doi.org/10.5812/ijp.112313
dc.identifier.urihttps://hdl.handle.net/20.500.13055/145
dc.identifier.volume31en_US
dc.identifier.wosWOS:000740231100001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynak.otherSCI-E - Science Citation Index Expandeden_US
dc.institutionauthorTuran, Volkan
dc.language.isoenen_US
dc.publisherTehran University of Medical Sciencesen_US
dc.relation.ispartofIranian Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAtherosclerosisen_US
dc.subjectCarotis Artery Intima-Media Thicknessen_US
dc.subjectGestational Tobacco Exposureen_US
dc.subjectLipid Profileen_US
dc.titleAssessment of carotid artery intima-media thickness and lipid profile in term neonates born to smoking mothersen_US
dc.typeArticleen_US
dspace.entity.typePublication

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