Browsing by Author "İşlek, Zeynep"
Now showing items 1-4 of 4
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Antileishmanial activity of BNIPDaoct- and BNIPDanon-loaded emulsomes on leishmania infantum parasites
İşlek, Zeynep; Üçışık, Mehmet Hikmet; Keskin, Elif; Onur Sucu, Bilgesu; Gomes-Alves, Ana G.; Tomás, Ana M.; Güzel, Mustafa; Şahin, Fikrettin (Frontiers Media S.A., 2022)Among bisnaphthalimidopropyl (BNIP) derivatives, BNIPDaoct and BNIPDanon recently came forward with antileishmanial activities beyond the standard, commercialized antileishmanial therapies. However, high-level toxicity on ... -
Delivery of curcumin within emulsome nanoparticles enhances the anti‑cancer activity in androgen‑dependent prostate cancer cell
Bolat, Zeynep Büşra; İşlek, Zeynep; Şahin, Fikrettin; Üçışık, Mehmet Hikmet (SpringerLink, 2023)Background Curcumin, a dietary polyphenol isolated from turmeric, is a potent phytochemical possessing intrinsic anticancer activities against various cancer types including prostate cancer. However, low water solubility ... -
Novel dual-fluorescent flow cytometric approach for quantification of macrophages infected with Leishmania infantum parasites
İşlek, Zeynep; Üçışık, Mehmet Hikmet; Şahin, Fikrettin (Cambridge University Press, 2022)Flow cytometry analysis emerges as an alternative methodology to microscopy for determination of the Leishmania-infection rates of macrophages. Various flow cytometric approaches have been established for the quantification ... -
The role of extracellular vesicles in immunomodulation and pathogenesis of Leishmania and other protozoan infections
İşlek, Zeynep; Bozkurt, Batuhan Turhan; Üçışık, Mehmet Hikmet; Şahin, Fikrettin (IntechOpen, 2022)Extracellular vesicles (EVs) have lately emerged as crucial mediators in parasite infections. Recent research suggests that protozoan parasites, including Leishmania, employ EVs as transport vehicles to deliver biologically ...
