Browsing by Author "Önal, Cem"
Now showing items 1-8 of 8
-
Analysis of capsaicinoids in chilli sauce with ultra fast liquid chromatography
Ceylan, Burhan; Önal, Cem; Önal, Armağan (Bezmialem Vakıf Üniversitesi, 2022)Objective: In current study, quantification of the capsaicinoids in chilli sauces based on a sensitive ultra fast liquid chromatography method and derivatization with dansyl chloride (DNS-Cl) was described. Capsaicinoids ... -
Development of an HPLC method for the determination of mesalazine in human plasma by fluorimetric derivatization and application to a prototype pharmacokinetic study
Ceylan, Burhan; Kepekçi Tekkeli, Evrim; Önal, Cem (Springer, 2022)In this study, a new, fast and sensitive HPLC method with fluorometric detection was developed for the determination of mesalazine in human plasma and applied to a pharmacokinetic study. Mesalazine was precolumn derivatized ... -
A liquid chromatographic analysis of deferasirox in human breast milk with fluorimetric detection
Önal, Cem; Tekkeli Kepekçi, Şerife Evrim; Sağıroğlu, Ali Asram (Springer, 2020)To determine deferasirox in human breast milk a novel, sensitive high-performance liquid chromatographic method with fluorescence detection has been developed. Precolumn derivatization process is applied to achieve fluorescent ... -
A liquid chromatographic analysis of gemifloxacin in pharmaceutical preparations using 4-bromomethyl-7-methoxycoumarin reagent
Önal, Cem (Galenos, 2021)Objective: In this study, analysis of gemifloxacin in pharmaceutical preparations was performed in the presence of 4-bromomethyl-7-methoxycoumarin reagent and dibenzo-18-crown-6 ether catalyst, by high-performance liquid ... -
Spectrofluorimetric analysis of ticagrelor in pharmaceutical formulations and spiked human plasma using 1-dimethylaminonaphthalene-5-sulphonyl chloride reagent
Önal, Cem; Tekkeli Şerife, Evrim Kepekçi (Marmara University Press, 2020)A sensitive method is presented for the determination of the ticagrelor (TCG) in human plasma and pharmaceutical preparations using 5-(dimethylamino)naphthalene-1-sulfonyl chloride (dansyl chloride). Ticagrelor contains a ... -
Spectrophotometric determination of erdosteine at capsule dosage forms
Önal, Cem; Dinçel, Demet (Galenos, 2021)Objective: Two simple, rapid and sensitive methods were developed for determination of Erdosteine (ERD) in pure form as well as in their pharmaceutical formulations. Methods: The methods were based on formation of colored ... -
Ultra fast liquid chromatographic analysis of nonsteroidal anti-inflammatory drugs with fluorimetric detection in tap water, urine, and pharmaceutical samples
Önal, Cem; Tırıs, Gizem; Kepekçi Tekkeli, Şerife Evrim; Önal, Armağan (Taylor and Francis, 2022)A novel analytical method based on ultra-fast liquid chromatography using fluorimetric detector was developed and validated for determination of non-steroidal anti-inflammatory drugs (NSAIDs) (ibuprofen (IBP), etodolac ... -
An UPLC method for the determination of sorafenib in human plasma by fluorimetric detection with pre-column derivatization and application to a pharmacokinetic study
Tırıs, Gizem; Kepekçi Tekkeli, Şerife Evrim; Önal, Cem; Ceylan, Burhan; Önal, Armağan (Editura Academiei Romane, 2022)This research presents a new, sensitive and selective UPLC method with fluorometric detection for the determination of sorafenib in human plasma and application of the method to a pharmacokinetic study. Sorafenib was ...
