Browsing by Author "Alpertunga, Buket"

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Molecular cardiotoxic effects of proteasome inhibitors Carfilzomib and Ixazomib and their combination with dexamethasone involve mitochondrial dysregulation

Jannuzzi, Ayşe Tarbin; Korkmaz, Nalan Sümeyra; Günaydın-Akyıldız, Ayşenur; Arslan Eseryel, Sema; Karademir Yılmaz, Betül; Alpertunga, Buket (Humana Press, 2023)

With the development and approval of new proteasome inhibitors, proteasome inhibition is increasingly recognized in cancer therapy. Besides successful anti-cancer effects in hematological cancers, side effects such as ...
Ubiquitin proteasomal system is a potential target of the toxic effects of organophosphorus flame retardant triphenyl phosphate

Jannuzzi, Ayse Tarbin; Yılmaz Göler, Ayşe Mine; Alpertunga, Buket (Elsevier, 2022)

The consumption of the widely used flame retardant Triphenyl phosphate (TPP) is increasing. It is now frequently detected in the environment and also domestically. Although the possibility of dermal exposure to TPP is quite ...