Browsing by Author "Gök Yurttaş, Asiye"
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Aza-BODIPY photosensitizer substituted with phthalonitrile groups: Synthesis, photophysical properties and in vitro tests for breast cancer
Özçelik, Şennur; Gök Yurttaş, Asiye; Kahveci, Muhammet U.; Sevim, Altuğ Mert; Gül, Ahmet (Elsevier, 2023)In photodynamic therapy (PDT), reactive oxygen species (ROS) are generated through dynamic interactions between light of a specific wavelength, a photosensitizer (PS) and molecular oxygen. Nowadays, there has been an ... -
Biyolojik tanıma elemanlarından proteinoidler kullanılarak empedans ölçüm yaklaşımıyla bakterilerin tespiti
Gök Yurttaş, Asiye (Bilecik Şeyh Edebali Üniversitesi, 2021)Günümüz dünyasında gelişen teknoloji ile su, gıda ve çevresel kirliliğin artmasıyla bu temel ihtiyaçların sağlık kontrolü oldukça zorlayıcıdır. Bu tür eksiklerin giderilmesi üzerine bir çalışma olmuştur. Bu amaçla iki temel ... -
The effects of thymoquinone on steroid-induced femoral head osteonecrosis: An experimental study in rats
Daşçı, Mustafa Fatih; Yaprak Saraç, Elif; Gök Yurttaş, Asiye; Atçı, Tolgahan; Uslu, Muhammed; Acar, Abdurrahman; Güleç, Mehmet Akif; Alagöz, Ender (Turkish Joint Diseases Foundation, 2022)Objectives: In this study, we aimed to evaluate the antioxidant, antiapoptotic, osteoblastic and hypolipidemic effects of thymoquinone (TQ) treatment on the steroid-induced osteonecrosis of femoral head (ONFH) model in ... -
The effects of zinc(II)phthalocyanine photosensitizers on biological activities of epitheloid cervix carcinoma cells and precise determination of absorbed fluence at a specific wavelength
Gök Yurttaş, Asiye; Sevim, Altuğ Mert; Çınar, Kamil; Yaşa Atmaca, Göknur; Erdoğmuş, Ali (Elsevier, 2022)Photodynamic therapy (PDT) is an alternative way to treat the cancer non-surgically with minimum harm, in which a specific light and light sensitive photosensitizer (PS) is used. This study deals with the utilization of ... -
Liposomes loaded with activatable disulfide bridged photosensitizer: Towards targeted and effective photodynamic therapy on breast cancer cells
Gök Yurttaş, Asiye; Gökduman, Kurtuluş; Hekim, Nezih (AMG Transcend Association, 2022)The motivation of the current study is to develop a strategy providing targeted and effective photodynamic therapy (PDT) on breast cancer cells by eliminating the limitations of PDT. For this purpose, a disulfide bridged ... -
Ozone combined with doxorubicin exerts cytotoxic and anticancer effects on Luminal-A subtype human breast cancer cell line
Karagülle, Onur Olgaç; Gök Yurttaş, Asiye (Associação Médica Brasileira, 2022)Objective: We aimed to examine the potential anticancer effects of ozone applied after chemotherapeutic treatment with different concentrations of doxorubicin in Luminal-A subtype of human breast cancer cell line (MCF-7) ... -
Role of p53 in human cancers
Açıkalın Çoşkun, Kübra; Tutar, Merve; Al, Mervenur; Gök Yurttaş, Asiye; Abay, Elif Cansu; Yürekli, Nazlıcan; Yeman Kıyak, Bercem; Uçar, Kezban; Tutar, Yusuf (IntechOpen, 2022)TP53 codes tumor protein 53-p53 that controls the cell cycle through binding DNA directly and induces reversible cell-cycle arrest. The protein activates DNA repair genes if mutated DNA will be repaired or activates ...