Browsing by Author "Gök Yurttaş, Asiye"
Now showing items 1-15 of 15
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Aza-BODIPY photosensitizer substituted with phthalonitrile groups: Synthesis, photophysical properties and in vitro tests for breast cancer
Özçelik, Şennur; Gök Yurttaş, Asiye; Kahveci, Muhammet U.; Sevim, Altuğ Mert; Gül, Ahmet (Elsevier, 2023)In photodynamic therapy (PDT), reactive oxygen species (ROS) are generated through dynamic interactions between light of a specific wavelength, a photosensitizer (PS) and molecular oxygen. Nowadays, there has been an ... -
Biyolojik tanıma elemanlarından proteinoidler kullanılarak empedans ölçüm yaklaşımıyla bakterilerin tespiti
Gök Yurttaş, Asiye (Bilecik Şeyh Edebali Üniversitesi, 2021)Günümüz dünyasında gelişen teknoloji ile su, gıda ve çevresel kirliliğin artmasıyla bu temel ihtiyaçların sağlık kontrolü oldukça zorlayıcıdır. Bu tür eksiklerin giderilmesi üzerine bir çalışma olmuştur. Bu amaçla iki temel ... -
The effects of thymoquinone on steroid-induced femoral head osteonecrosis: An experimental study in rats
Daşçı, Mustafa Fatih; Yaprak Saraç, Elif; Gök Yurttaş, Asiye; Atçı, Tolgahan; Uslu, Muhammed; Acar, Abdurrahman; Güleç, Mehmet Akif; Alagöz, Ender (Turkish Joint Diseases Foundation, 2022)Objectives: In this study, we aimed to evaluate the antioxidant, antiapoptotic, osteoblastic and hypolipidemic effects of thymoquinone (TQ) treatment on the steroid-induced osteonecrosis of femoral head (ONFH) model in ... -
The effects of zinc(II)phthalocyanine photosensitizers on biological activities of epitheloid cervix carcinoma cells and precise determination of absorbed fluence at a specific wavelength
Gök Yurttaş, Asiye; Sevim, Altuğ Mert; Çınar, Kamil; Yaşa Atmaca, Göknur; Erdoğmuş, Ali (Elsevier, 2022)Photodynamic therapy (PDT) is an alternative way to treat the cancer non-surgically with minimum harm, in which a specific light and light sensitive photosensitizer (PS) is used. This study deals with the utilization of ... -
Exploring the molecular mechanism of linagliptin in osteosarcoma cell lines for anti-cancer activity
Gök Yurttaş, Asiye; Daşçı, Mustafa Fatih (Elsevier, 2023)Background: Finding new applications for widely used current drugs is a fast and effective technique for discovering new anticancer chemicals. Osteosarcoma (OS), the most prevalent form of bone cancer, has several side ... -
Genetic deviation associated with photodynamic therapy in hela cell
Gök Yurttaş, Asiye; Okat, Zehra; Elgün, Tuğba; Uçar Çifçi, Kezban; Sevim, Altuğ Mert (Elsevier, 2023)Photodynamic therapy (PDT) is a crucial method that is used in cancer treatment. Entering the program for PDT selection today gives a new direction. The main therapeutic effect is the production of singlet oxygen (1O2), ... -
Kolorektal kanserde kullanılan biyobelirteçler
Gök Yurttaş, Asiye (Kolorektal Cerrahi Hastalıklar, 2020)Kolorektal kanser (KK), hem erkek hem de kadınlarda meydana gelen en yaygın ve ölümcül malignitelerden biri olarak kabul edilir. Yaygın prevalansı, KK için yeni tanısal ve prognostik biyobelirteçlere olan ihtiyacı ... -
Liposomes loaded with activatable disulfide bridged photosensitizer: Towards targeted and effective photodynamic therapy on breast cancer cells
Gök Yurttaş, Asiye; Gökduman, Kurtuluş; Hekim, Nezih (AMG Transcend Association, 2022)The motivation of the current study is to develop a strategy providing targeted and effective photodynamic therapy (PDT) on breast cancer cells by eliminating the limitations of PDT. For this purpose, a disulfide bridged ... -
Molecular mechanisms of heat shock proteins in distinct diseases
Yürekli, Nazlıcan; Tutar, Merve; Niyazov, Laziz; Sağır, Fatma; Açıkalın Coşkun, Kübra; Al, Mervenur; Uçar Çifçi, Kezban; Abay, Cansu; Gök Yurttaş, Asiye; Okat, Zehra; Tutar, Yusuf (Scientific Scholar, 2023)Heat shock proteins (HSPs) modulate the molecular mechanics of cells and cellular systems. Properly folded proteins are required for cellular processes and organisms use molecular mechanics to keep substrate proteins in ... -
Novel targeted therapeutic approaches to cancers
Gök Yurttaş, Asiye; Gök Yurttaş, Asiye (Özgür Yayınları, 2023)Kanser, modern toplumun en yaygın ve korkulan hastalıklarından biridir. Son yıllarda insidansı giderek artmaktadır. Kanserin moleküler özelliklerinin anlaşılmaya başlamasıyla birlikte çalışmalar hedefe yönelik tedaviler ... -
Ozone combined with doxorubicin exerts cytotoxic and anticancer effects on Luminal-A subtype human breast cancer cell line
Karagülle, Onur Olgaç; Gök Yurttaş, Asiye (Associação Médica Brasileira, 2022)Objective: We aimed to examine the potential anticancer effects of ozone applied after chemotherapeutic treatment with different concentrations of doxorubicin in Luminal-A subtype of human breast cancer cell line (MCF-7) ... -
P. aeruginosa bakterisinin vitamin B kompleksi ve kırmızı lazer kullanılarak inaktive edilmesi
Gök Yurttaş, Asiye; Çınar, Kamil (Süleyman Demirel Üniversitesi, 2022)Son yıllarda anti-bakteriyel direnç olgusu, bakterilerin neden olduğu hastalıklarla mücadelede daha fazla sorun haline gelmiştir. Biz bu çalışmayla, açık yara ve yanıkların fırsatçı patojeni olan Pseudomonas aeruginosayı ... -
Photodyanamic therapy in the cervical cancer
Gök Yurttaş, Asiye (Özgür Yayınları, 2023)Cancer is one of the most common and feared illnesses in modern society. Its prevalence has been gradually rising in recent years. The fourth most common malignancy in women worldwide is cervical cancer (CC). Surgery, ... -
Role of p53 in human cancers
Açıkalın Çoşkun, Kübra; Tutar, Merve; Al, Mervenur; Gök Yurttaş, Asiye; Abay, Elif Cansu; Yürekli, Nazlıcan; Yeman Kıyak, Bercem; Uçar, Kezban; Tutar, Yusuf (IntechOpen, 2022)TP53 codes tumor protein 53-p53 that controls the cell cycle through binding DNA directly and induces reversible cell-cycle arrest. The protein activates DNA repair genes if mutated DNA will be repaired or activates ... -
Vitamin B kompleksinin fotodinamik terapiyle kolon kanserine etkisi
Gök Yurttaş, Asiye; Çınar, Kamil (Süleyman Demirel Üniversitesi, 2023)Amaç: Kolon kanserleri, hastanın yaşam kalitesini derinden etkileyen ve çeşitli komplikasyonlarla ilişkili kronik ölümcül bir hastalıktır. Vitamin B kompleksi, gıda takviyesi olarak alındığında olumlu anti-inflamatuar ...
