Prognostic nutritional index versus cally, conut, and car for predicting restenosis after endovascular treatment of superficial femoral artery chronic total occlusion

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dc.authorid0000-0002-3872-2063
dc.authorid0009-0005-9835-4919
dc.authorid0009-0009-5357-9144
dc.authorid0000-0002-2587-9707
dc.authorid0000-0001-6767-6935
dc.contributor.authorİskender, Hakan
dc.contributor.authorKılıç, Ömer Abdulbaki
dc.contributor.authorJabrayilzade, Jabrayil
dc.contributor.authorVeyisoğlu, İbrahim
dc.contributor.authorToprak, Cüneyt
dc.contributor.authorÇakmak, Ender Özgün
dc.date.accessioned2026-10-21T15:59:57Z
dc.date.available2026-10-21T15:59:57Z
dc.date.issued2026
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractBackground: Inflammation- and nutrition-based indices have been associated with adverse outcomes after peripheral endovascular interventions, but their comparative performance re mains unclear. We compared the associations and discriminatory performance of the prognostic nutritional index (PNI), C-reactive protein—albumin—lymphocyte (CALLY) index, controlling nutritional status (CONUT) score, and C-reactive protein-to-albumin ratio (CAR) in relation to 6-month restenosis after endovascular treatment of superficial femoral artery chronic total occlu sion (SFA CTO). Methods: This retrospective cohort included 227 technically successful SFA CTO procedures performed between 2015 and 2021 with imaging-based 6-month restenosis assessment. The 4 indices were compared using receiver operating characteristic analysis and separate multivari able logistic regression models adjusted for clinical and lesion-related factors. Multiplicity correc tion and patient-cluster bootstrap internal validation were performed. Results: Restenosis occurred in 79 procedures (34.8%). PNI showed the highest discrimination (area under the curve [AUC] 0.728; 95% confidence interval [CI]: 0.662—0.794), compared with CONUT (0.625), CALLY (0.582), and CAR (0.568). After multivariable adjustment and multiplic ity correction, PNI (adjusted odds ratio [OR] 2.72 per 1-SD worsening; 95% CI 1.78—4.14) and CONUT (adjusted OR 1.61; 95% CI 1.17—2.22) remained independently associated with reste nosis, whereas CALLY and CAR did not. Adding PNI to the clinical base model increased the AUC from 0.670 to 0.782 and reduced the Brier score from 0.209 to 0.178. The improvement persisted after bootstrap validation (optimism-corrected AUC 0.740).
dc.identifier.citationİskender, H., Kılıç, Ö. A., Jabrayilzade, J., Veyisoğlu, İ., Toprak, C., & Çakmak, E. Ö. (2026). Prognostic nutritional index versus cally, conut, and car for predicting restenosis after endovascular treatment of superficial femoral artery chronic total occlusion. Annals of Vascular Surgery, 134, pp. 248-260. https://doi.org/10.1016/j.avsg.2026.09.002
dc.identifier.doi10.1016/j.avsg.2026.09.002
dc.identifier.endpage260
dc.identifier.issn0890-5096
dc.identifier.issn1615-5947
dc.identifier.pmidPMID: 42754221
dc.identifier.scopus2-s2.0-105052752758
dc.identifier.scopusqualityQ2
dc.identifier.startpage248
dc.identifier.urihttps://doi.org/10.1016/j.avsg.2026.09.002
dc.identifier.urihttps://hdl.handle.net/20.500.13055/1674
dc.identifier.volume134
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynak.otherSCI-E - Science Citation Index Expanded
dc.institutionauthorÇakmak, Ender Özgün
dc.institutionauthorid0000-0001-6767-6935
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofAnnals of Vascular Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.titlePrognostic nutritional index versus cally, conut, and car for predicting restenosis after endovascular treatment of superficial femoral artery chronic total occlusion
dc.typeArticle
dspace.entity.typePublication

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