The impact of home-based telerehabilitation pranayama on sleep quality and wellbeing in mild to moderate obstructive sleep apnea syndrome. A randomized controlled trial

dc.authorid0000-0002-0079-0976
dc.authorid0000-0002-2901-2967
dc.authorid0000-0001-7030-0787
dc.authorid0000-0003-0762-6228
dc.authorid0000-0003-3764-2421
dc.authorid0000-0002-2993-243X
dc.contributor.authorKaçar Akkoç, Zeynep
dc.contributor.authorDemir, Rengin
dc.contributor.authorMustafaoğlu, Rüstem
dc.contributor.authorÖnder, Ömer Önder
dc.contributor.authorNaci, Baha
dc.contributor.authorAtahan, Ersan
dc.date.accessioned2026-04-21T13:49:34Z
dc.date.available2026-04-21T13:49:34Z
dc.date.issued2026
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı
dc.description.abstractBackground Obstructive sleep apnea syndrome (OSAS) is a common disorder that causes repeated airway obstruction, disrupted breathing, and fragmented sleep. This study aimed to investigate the effects of Pranayama on sleep quality, daytime sleepiness, quality of life, fatigue, depression, and anxiety in patients with OSAS. Methods This study was designed as an open-label, prospective, randomized controlled trial. OSAS patients meeting the inclusion criteria were randomly assigned to either an Intervention group or a Control group. Pranayama training was applied to the Intervention group for 8 weeks, 7 days a week, and 3 times a day for 15 min. In addition, a single 15-minute session, 3 days a week, was conducted online under the supervision of a physiotherapist. The control group did not receive any intervention. Primary outcome was sleep quality (Pittsburgh Sleep Quality Index, PSQI). Secondary outcomes included daytime sleepiness (Epworth Sleepiness Scale, ESS), Fatigue Severity Scale (FSS), Functional Outcomes of Sleep Questionnaire (FOSQ), Nottingham Health Profile (NHP), and Hospital Anxiety and Depression Scale (HADS). All outcome measures were assessed at baseline and reassessed after the 8-week intervention period. Results Thirty-eight OSAS patients meeting the inclusion criteria were randomly assigned to either an Intervention group (n = 19) or a Control group (n = 19). Four participants (two in each group) were lost to follow-up, leaving the data of 34 participants (17 per group) available for inclusion in the final analysis. In the intervention group, PSQI scores decreased from 9.12 ± 4.71 to 6.88 ± 4.45 (p < 0.001), whereas no improvement was observed in the control group. Regarding the primary outcome, the reduction in PSQI scores was significantly greater in the intervention group than in the control group (p < 0.001). The ESS scores also decreased significantly in the intervention group, from 9.41 ± 6.15 to 7.41 ± 6.18 (p = 0.006, with a significant between-group difference (p < 0.001). Fatigue severity decreased in the intervention group (FSS change: 0.53 ± 0.70; p = 0.006), with a significant between-group difference (p = 0.037). The FOSQ score improved markedly, with significant gains in FOSQ total score (− 0.38 ± 0.25 vs. 0.14 ± 0.22 in controls; p < 0.001) and in activity level and vigilance subdomains (both p < 0.001). The HADS-anxiety scores decreased by 1.94 ± 3.94 (p = 0.059) and depression scores by 3.06 ± 2.05 (p < 0.001) in the intervention group, with significant between-group differences for both anxiety (p = 0.008) and depression (p < 0.001). Conclusion Pranayama was an effective adjunct therapy for these OSAS patients, and incorporating it into treatment strategies may enhance patient outcomes. Clinical trial registration number/date NCT04632147/22.10.2020.
dc.identifier.citationKaçar Akkoç, Z., Demir, R., Mustafaoğlu, R., Önder, Ö. Ö., Naci, B., & Atahan, E. (2026). The impact of home-based telerehabilitation pranayama on sleep quality and wellbeing in mild to moderate obstructive sleep apnea syndrome. A randomized controlled trial. BioPsychoSocial Medicine, https://doi.org/10.1186/s13030-026-00359-x
dc.identifier.doi10.1186/s13030-026-00359-x
dc.identifier.issn1751-0759
dc.identifier.pmidPMID: 41992331
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1186/s13030-026-00359-x
dc.identifier.urihttps://hdl.handle.net/20.500.13055/1440
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynak.otherSSCI - Social Science Citation Index
dc.institutionauthorÖnder, Ömer Önder
dc.institutionauthorid0000-0003-0762-6228
dc.language.isoen
dc.publisherBioMed Central
dc.relation.ispartofBioPsychoSocial Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectObstructive Sleep Apnea
dc.subjectSleep Quality
dc.subjectQuality of Life
dc.subjectDaytime Sleepiness
dc.subjectFatigue
dc.subjectDepression
dc.titleThe impact of home-based telerehabilitation pranayama on sleep quality and wellbeing in mild to moderate obstructive sleep apnea syndrome. A randomized controlled trial
dc.typeArticle
dspace.entity.typePublication

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