Antibacterial mechanism with consequent cytotoxicity of different reinforcements in biodegradable magnesium and zinc alloys: A review

Basit Öğe Kaydı
dc.authorid0000-0002-7797-604Xen_US
dc.authorscopusid6507405286en_US
dc.authorwosidB-3144-2011en_US
dc.contributor.authorShahed, Chowdhury Ahmed
dc.contributor.authorAhmad, Faiz
dc.contributor.authorGünister, Ebru
dc.contributor.authorFoudzi, Farhana Mohd
dc.contributor.authorAli, Saad
dc.contributor.authorMalik, Khurshid
dc.contributor.authorHarun, Wan Sharuzi Wan
dc.date.accessioned2023-10-05T09:15:14Z
dc.date.available2023-10-05T09:15:14Z
dc.date.issued2023en_US
dc.departmentFakülteler, Mühendislik ve Doğa Bilimleri Fakültesi, Makine Mühendisliği Bölümüen_US
dc.descriptionUniversiti Teknologi PETRONAS (UTP) -- 015LC0-336en_US
dc.description.abstractBenefits achieved by the biodegradable magnesium (Mg) and zinc (Zn) implants could be suppressed due to the invasion of infectious microbial, common bacteria, and fungi. Postoperative medications and the antibacterial properties of pure Mg and Zn are insufficient against biofilm and antibiotic-resistant bacteria, bringing osteomyelitis, necrosis, and even death. This study evaluates the antibacterial performance of biodegradable Mg and Zn alloys of different reinforcements, including silver (Ag), copper (Cu), lithium (Li), and gallium (Ga). Copper ions (Cu2+) can eradicate biofilms and antibiotic-resistant bacteria by extracting electrons from the cellular structure. Silver ion (Ag+) kills bacteria by creating bonds with the thiol group. Gallium ion (Ga3+) inhibits ferric ion (Fe3+) absorption, leading to nutrient deficiency and bacterial death. Nanoparticles and reactive oxygen species (ROS) can penetrate bacteria cell walls directly, develop bonds with receptors, and damage nucleotides. Antibacterial action depends on the alkali nature of metal ions and their degradation rate, which often causes cytotoxicity in living cells. Therefore, this review emphasizes the insight into degradation rate, antibacterial mechanism, and their consequent cytotoxicity and observes the correlation between antibacterial performance and oxidation number of metal ions.en_US
dc.identifier.citationShahed, C. A., Ahmad, F., Günister, E., Foudzi, F. M., Ali, S., Malik, K., & Harun, W. S.W. (2023). Antibacterial mechanism with consequent cytotoxicity of different reinforcements in biodegradable magnesium and zinc alloys: A review. Journal of Magnesium and Alloys, 11(9), pp. 3038-3058. https://doi.org/10.1016/j.jma.2023.08.018en_US
dc.identifier.doi10.1016/j.jma.2023.08.018en_US
dc.identifier.endpage3058en_US
dc.identifier.issn2213-9567
dc.identifier.issue9en_US
dc.identifier.scopus2-s2.0-85171687024en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage3038en_US
dc.identifier.urihttps://doi.org/10.1016/j.jma.2023.08.018
dc.identifier.urihttps://hdl.handle.net/20.500.13055/553
dc.identifier.volume11en_US
dc.identifier.wosWOS:001107583500001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynak.otherSCI-E - Science Citation Index Expandeden_US
dc.institutionauthorGünister, Ebru
dc.language.isoenen_US
dc.publisherKeAi Communications Co.en_US
dc.relation.ispartofJournal of Magnesium and Alloysen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiodegradable Materialsen_US
dc.subjectBiomedical Implantsen_US
dc.subjectAntibacterial Mechanismen_US
dc.subjectCytotoxicityen_US
dc.subjectReactive Oxygen Speciesen_US
dc.titleAntibacterial mechanism with consequent cytotoxicity of different reinforcements in biodegradable magnesium and zinc alloys: A reviewen_US
dc.typeReview Articleen_US
dspace.entity.typePublication

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Antibacterial mechanism with consequent cytotoxicity of different reinforcements in biodegradable magnesium and zinc alloys A review.pdf
Boyut:
5.27 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Kapalı Erişim
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Makine Mühendisliği Bölümü Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu