Development of an HPLC-UV method for the simultaneous determination of allantoin and D-panthenol in cosmetic products containing Aloe vera extracts
Yükleniyor...
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Akadémiai Kiadó (AK)
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
A simple, fast and selective analytical method has been developed for the simultaneous determination of allantoin and D-panthenol in cosmetic products containing Aloe vera extracts. The proposed method depends on reversed-phase liquid chromatography with isocratic flow profile of the mobile phase composed of acetonitrile–10 mM phosphoric acid (pH 2.5) (85:15, v/v), with a C18 column at 30 8C. The analytes were detected with UV–vis. detector at 210 nm. The injection volume was 20 μL. The linearity ranges were found to be 0.2–20 and 0.1–10 μg mL 1 for allantoin and D-panthenol, respec tively. LOD values were found to be 0.07 μg mL 1 and 0.03 μg mL 1 , LOQ values were found to be 0.2 and 0.1 μg mL 1 for allantoin and D-panthenol, respectively. No interference was observed from concomitants. The developed method was applied to the analysis of 10 different type cosmetic products. It is foreseen that the method will be able to be used in order to carry out routine analysis, quality control and standardization in cosmetic products containing allantoin and D-panthenol.
Açıklama
Anahtar Kelimeler
Allantoin, D-Panthenol, High Performance Liquid Chromatography, Aloe Vera, Cosmetic Products, UV Detection
Kaynak
Acta Chromatographica
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
Sayı
Künye
Ceylan, B., & Kepekçi Tekkeli, Ş. E. (2024). Development of an HPLC-UV method for the simultaneous determination of allantoin and D-panthenol in cosmetic products containing Aloe vera extracts. Acta Chromatographica, pp. 1-6. https://doi.org/10.1556/1326.2024.01216
