Development of an HPLC-UV method for the simultaneous determination of allantoin and D-panthenol in cosmetic products containing Aloe vera extracts

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dc.authorid0000-0002-1871-017Xen_US
dc.authorscopusid49964600400en_US
dc.authorwosidA-3672-2016en_US
dc.contributor.authorCeylan, Burhan
dc.contributor.authorKepekçi Tekkeli, Şerife Evrim
dc.date.accessioned2024-05-24T06:07:42Z
dc.date.available2024-05-24T06:07:42Z
dc.date.issued2024en_US
dc.departmentFakülteler, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Analitik Kimya Ana Bilim Dalıen_US
dc.description.abstractA simple, fast and selective analytical method has been developed for the simultaneous determination of allantoin and D-panthenol in cosmetic products containing Aloe vera extracts. The proposed method depends on reversed-phase liquid chromatography with isocratic flow profile of the mobile phase composed of acetonitrile–10 mM phosphoric acid (pH 2.5) (85:15, v/v), with a C18 column at 30 8C. The analytes were detected with UV–vis. detector at 210 nm. The injection volume was 20 μL. The linearity ranges were found to be 0.2–20 and 0.1–10 μg mL 1 for allantoin and D-panthenol, respec tively. LOD values were found to be 0.07 μg mL 1 and 0.03 μg mL 1 , LOQ values were found to be 0.2 and 0.1 μg mL 1 for allantoin and D-panthenol, respectively. No interference was observed from concomitants. The developed method was applied to the analysis of 10 different type cosmetic products. It is foreseen that the method will be able to be used in order to carry out routine analysis, quality control and standardization in cosmetic products containing allantoin and D-panthenol.en_US
dc.identifier.citationCeylan, B., & Kepekçi Tekkeli, Ş. E. (2024). Development of an HPLC-UV method for the simultaneous determination of allantoin and D-panthenol in cosmetic products containing Aloe vera extracts. Acta Chromatographica, pp. 1-6. https://doi.org/10.1556/1326.2024.01216en_US
dc.identifier.doi10.1556/1326.2024.01216en_US
dc.identifier.endpage6en_US
dc.identifier.issn1233-2356
dc.identifier.issn2083-5736
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://doi.org/10.1556/1326.2024.01216
dc.identifier.urihttps://hdl.handle.net/20.500.13055/708
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynak.otherSCI-E - Science Citation Index Expandeden_US
dc.institutionauthorKepekçi Tekkeli, Şerife Evrim
dc.language.isoenen_US
dc.publisherAkadémiai Kiadó (AK)en_US
dc.relation.ispartofActa Chromatographicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAllantoinen_US
dc.subjectD-Panthenolen_US
dc.subjectHigh Performance Liquid Chromatographyen_US
dc.subjectAloe Veraen_US
dc.subjectCosmetic Productsen_US
dc.subjectUV Detectionen_US
dc.titleDevelopment of an HPLC-UV method for the simultaneous determination of allantoin and D-panthenol in cosmetic products containing Aloe vera extractsen_US
dc.typeArticleen_US
dspace.entity.typePublication

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