Cysteine challenge test as a novel diagnostic tool to distinguish oral halitosis

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dc.authorid0000-0002-0138-251Xen_US
dc.contributor.authorAydın, Murat
dc.contributor.authorGünay, İsmail
dc.date.accessioned2022-03-04T09:51:05Z
dc.date.available2022-03-04T09:51:05Z
dc.date.issued2022en_US
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyofizik Ana Bilim Dalıen_US
dc.description.abstractBackground: The cysteine challenge test is often used to check the H2S production capacity of the mouth. Patients with oral halitosis group (n = 305) or non-oral halitosis group (n = 191) and healthy individuals (control group, n = 102) were compared with each other to identify any possible relationship between initial and cysteine-induced oral H2S concentrations. Subjects and Method: The medical records of 598 participants were reviewed retrospectively. Oral H2S concentrations before (pre-CR) and after cysteine rinse (post-CR) with 5 mL of 20 mmol L-cysteine solution for 30 s were compared. Results: Pre-CR H2S concentrations were >0.8 ppm in 75.1% of oral group patients but less than <0.8 ppm in 87.3% of the non-oral group and 86.9% of controls. After cysteine rinse, oral H2S concentrations exceeded 12 ppm in 72% of the oral halitosis patients but were lower in 88% of non-oral group and 99% of controls. Whilst post-CR/pre-CR ratio was >12 in 74.5% of the oral group, it was <12 in 81.7% of the non-oral group and 83.4% of controls. Conclusion: Cysteine challenge test can be used as a diagnostic tool to identify an individual’s tendency to produce oral malodor, not only to quantify momentary halitosis level.en_US
dc.identifier.citationAydın, M., & Günay, İ. (2022). Cysteine challenge test as a novel diagnostic tool to distinguish oral halitosis. Australian Dental Journal, 67(1), pp. 69-75. https://doi.org/10.1111/adj.12884 ‌en_US
dc.identifier.doi10.1111/adj.12884en_US
dc.identifier.endpage75en_US
dc.identifier.issue1en_US
dc.identifier.pmidPMID: 34729788en_US
dc.identifier.scopus2-s2.0-85119035933en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage69en_US
dc.identifier.urihttps://doi.org/10.1111/adj.12884
dc.identifier.urihttps://hdl.handle.net/20.500.13055/187
dc.identifier.volume67en_US
dc.identifier.wosWOS:000719392500001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynak.otherSCI-E - Science Citation Index Expandeden_US
dc.institutionauthorGünay, İsmail
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAustralian Dental Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBad Breathen_US
dc.subjectDifferential Diagnosisen_US
dc.subjectHalitosisen_US
dc.subjectHydrogen Sulphideen_US
dc.subjectOral Malodoren_US
dc.titleCysteine challenge test as a novel diagnostic tool to distinguish oral halitosisen_US
dc.typeArticleen_US
dspace.entity.typePublication

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