Patients experienced serious adverse reactions within one hour of hematopoietic stem-cell infusion

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dc.authorid0000-0002-0335-2330en_US
dc.authorscopusid57478196200en_US
dc.authorwosidHIR-7894-2022en_US
dc.contributor.authorMeriç, Neslihan
dc.contributor.authorParmaksız, Ayhan
dc.contributor.authorGülbaş, Zafer
dc.date.accessioned2022-12-29T12:17:41Z
dc.date.available2022-12-29T12:17:41Z
dc.date.issued2023en_US
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyoistatistik Ana Bilim Dalıen_US
dc.description.abstractMethods: SARs were examined occurred within 1 hour after initiating HSC product infusions in all HSCT done in Turkey's Anadolu Medical Center Hospital accredited for HSCTs between 2013 and 2015, targeting 315 patients. Results: SARs were carefully evaluated in this study based on a comparison of the amount of stem cells infused, age, frozen sample (FS) / non-frozen samples (NFS) between HSCs sources. Rate of SARs is significantly higher in FS infusions supports the hypothesis that DMSO plays an important role in the development of SAR. Conclusion: The rate of SARs is significantly higher in infusions given using FSs confirms the hypothesis that the preservative agent DMSO plays an important role in the development of SAR. Our study provides guidance for future studies on the necessity of reducing the amount of DMSO in the HSCT product and using other alternative freezing agents instead of DMSO. © 2022 Société française de transfusion sanguine (SFTS)en_US
dc.identifier.citationMeriç, N., Parmaksız, A., & Gülbaş, Z. (2023). Patients experienced serious adverse reactions within one hour of hematopoietic stem-cell infusion. Transfusion Clinique et Biologique, 30(1), pp. 82-86. https://doi.org/10.1016/j.tracli.2022.08.141en_US
dc.identifier.doi10.1016/j.tracli.2022.08.141en_US
dc.identifier.endpage86en_US
dc.identifier.issn1246-7820
dc.identifier.issue1en_US
dc.identifier.pmidPMID: 35987476en_US
dc.identifier.scopus2-s2.0-85137741478en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage82en_US
dc.identifier.urihttps://doi.org/10.1016/j.tracli.2022.08.141
dc.identifier.urihttps://hdl.handle.net/20.500.13055/343
dc.identifier.volume30en_US
dc.identifier.wosWOS:000927407600001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynak.otherSCI-E - Science Citation Index Expandeden_US
dc.institutionauthorParmaksız, Ayhan
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofTransfusion Clinique et Biologiqueen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCryopreservationen_US
dc.subjectDMSOen_US
dc.subjectHSCTen_US
dc.subjectSerious Adverse Reactionsen_US
dc.titlePatients experienced serious adverse reactions within one hour of hematopoietic stem-cell infusionen_US
dc.typeArticleen_US
dspace.entity.typePublication

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