Palatal donor site management using tissue adhesives with adjunctive coconut oil in a randomized clinical trial

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dc.authorid0000-0001-7986-7085
dc.authorid0009-0000-0325-539X
dc.authorid0000-0001-6508-9016
dc.authorid0000-0002-0335-2330
dc.authorid0000-0001-7409-1484
dc.authorid0000-0001-6695-2133
dc.contributor.authorYılmaz, Melis
dc.contributor.authorBalcı, Nur
dc.contributor.authorGünay, Bestegül
dc.contributor.authorParlak, Hanife Merva
dc.contributor.authorParmaksız, Ayhan
dc.contributor.authorToygar, Hilal
dc.contributor.authorKeçeli, Hüseyin Gencay
dc.date.accessioned2025-09-02T10:35:38Z
dc.date.available2025-09-02T10:35:38Z
dc.date.issued2025
dc.departmentFakülteler, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümü
dc.description.abstractManagement of the complications occurring in the donor area after epithelialized gingival graft (EGG) harvesting still poses a challenge for clinicians. This study aimed to evaluate the influence of gelatin sponge (GS), cyanoacrylate (CY), and coconut oil (CO) combination in comparison with GS+CY in donor site management. Fifty EGG were harvested from the lateral palate in 50 patients, who were subsequently randomized to receive the GS+CY (control) or GS+CY+CO combination (test). Postoperative pain perception (PP), quantity of analgesics (QA), epithelization level (EL), color match (CM), sensation loss (SL), postoperative discomfort (PD), and delayed bleeding (DB) were evaluated. The GS+CY+CO group showed lower PP scores compared to the GS+CY (p<0.05). The QA intake was similar in both groups. On day 14, the GS+CY+CO group achieved 80% full EL rate, which was higher than the GS+CY group (32%) (p=0.002). CM scores were higher in the GS+CY+CO group at all follow up periods (p<0.001). Both groups reported similar SL, PD, and DB values (p>0.05). GS+CY+CO combination is more effective in reducing pain compared to GS+CO in donor site management after EGG harvesting. Additionally, GS+CY+CO combination may accelerate epithelialization and improve color match compared to GS+CY alone.
dc.identifier.citationYılmaz, M., Balcı, N., Günay, B., Parlak, H. M., Parmaksız, A., Toygar, H., & Keçeli, H. G. (2025). Palatal donor site management using tissue adhesives with adjunctive coconut oil in a randomized clinical trial. Scientific Reports, 15(1), pp. 1-9. https://doi.org/10.1038/s41598-025-17071-5
dc.identifier.doi10.1038/s41598-025-17071-5
dc.identifier.endpage9
dc.identifier.issn2045-2322
dc.identifier.issue1
dc.identifier.pmidPMID: 40858855
dc.identifier.scopus2-s2.0-105014141926
dc.identifier.scopusqualityQ1
dc.identifier.startpage1
dc.identifier.urihttps://doi.org/10.1038/s41598-025-17071-5
dc.identifier.urihttps://hdl.handle.net/20.500.13055/1102
dc.identifier.volume15
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynak.otherSCI-E - Science Citation Index Expanded
dc.institutionauthorParmaksız, Ayhan
dc.institutionauthorid0000-0002-0335-2330
dc.language.isoen
dc.publisherSpringer Nature
dc.relation.ispartofScientific Reports
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAbsorbable Gelatin Sponge
dc.subjectCyanoacrylates
dc.subjectCoconut Oil
dc.subjectWound Healing
dc.subjectDonor Site
dc.subjectTissue Grafts
dc.titlePalatal donor site management using tissue adhesives with adjunctive coconut oil in a randomized clinical trial
dc.typeArticle
dspace.entity.typePublication

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