The role of exosomal micrornas in cancer metastasis: An in-depth guide

Basit Öğe Kaydı
dc.authorid0009-0006-8386-8957
dc.authorid0000-0002-8919-0482
dc.contributor.authorTahan, Rana
dc.contributor.authorYazıcı, Hülya
dc.date.accessioned2026-01-07T12:06:44Z
dc.date.available2026-01-07T12:06:44Z
dc.date.issued2025
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Ana Bilim Dalı
dc.description.abstractExosomes and their contents play a vital role in forming a unique communication system that carries and transmits signal molecules, which alter the physiological state of cells and are linked to the on set and progression of numerous diseases including cancers. Focusing on exosomal cargo, microRNAs (miRNAs), which are small non-coding, single-stranded RNAs that regulate gene expression of target genes, are suggested to be transferred via exosomes in a selective manner that facilitates cancer progres sion and dissemination. In this context and through ongoing cancer research, researchers have currently been focusing on exosomal microRNA as a specific communication message delivered from cancer cells to the other cells that plays a crucial role in the immune response, tumor migration, tumor cell invasion, and development of metastasis In this review, we aim to evaluate the expected role of exosome-derived microRNAs in the development of cancer metastasis and their possible role of molecular markers in metastasis sites by the current literature on cancer research.
dc.identifier.citationTahan, R., & Yazıcı, H. (2025). The role of exosomal micrornas in cancer metastasis: An in-depth guide. Turkish Journal of Oncology, 40(4), pp. 318-331. https://doi.org/10.5505/tjo.2025.4550
dc.identifier.doi10.5505/tjo.2025.4550
dc.identifier.endpage331
dc.identifier.issn2717-8978
dc.identifier.issn1300-7467
dc.identifier.issue4
dc.identifier.scopusqualityQ4
dc.identifier.startpage318
dc.identifier.urihttps://doi.org/10.5505/tjo.2025.4550
dc.identifier.urihttps://hdl.handle.net/20.500.13055/1233
dc.identifier.volume40
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynak.otherESCI - Emerging Sources Citation Index
dc.institutionauthorYazıcı, Hülya
dc.institutionauthorid0000-0002-8919-0482
dc.language.isoen
dc.publisherTürk Radyasyon Onkolojisi Derneği
dc.relation.ispartofTurkish Journal of Oncology
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCancer
dc.subjectExosomal MicroRNAs
dc.subjectMetastasis
dc.titleThe role of exosomal micrornas in cancer metastasis: An in-depth guide
dc.typeReview
dspace.entity.typePublication

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