Effect of plaque-disclosing agents on biofilm removal: Single-center randomized trial in fourth-year dental students

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dc.authorid0000-0003-0454-9044
dc.authorid0000-0002-8440-367X
dc.authorid0000-0001-5489-6883
dc.authorid0000-0001-7439-5015
dc.contributor.authorBallı Akgöl, Beyza
dc.contributor.authorBayram, Merve
dc.contributor.authorÜstün, Nilüfer
dc.contributor.authorAksaka, Nurcan
dc.date.accessioned2026-04-13T13:11:00Z
dc.date.available2026-04-13T13:11:00Z
dc.date.issued2026
dc.departmentFakülteler, Diş Hekimliği Fakültesi, Klinik Bilimler Bölümü, Pedodonti Ana Bilim Dalı
dc.description.abstractBackground To assess whether plaque-disclosing agents (PDA) improve self-performed mechanical plaque removal and gingival health compared with standard instruction alone in dental students. Design/Setting Single-center, parallel-group randomized controlled trial (1:1), Istanbul Medipol University (Oct 2023–Jan 2024). Participants 124 fourth-year dental students (age 20–30 years) randomized to test (n=62) or control (n=62). Interventions Both groups received standardized oral-hygiene instruction (Modified Bass; interdental cleaning guidance). The test group additionally received PDA before brushing as a visual aid; all outcomes were measured after triple rinsing. Primary outcome (prespecified) Between-group difference in change (Δ) in Plaque Index (PI) from baseline to week 1. Secondary outcomes ΔPI baseline→post-brushing and baseline→month 1; ΔGingival Index (GI) baseline→week 1 and baseline→month 1. Masking Outcome assessor blinded at the time of measurement (after rinsing). Results All 124 randomized participants completed follow-up and were analyzed. Both groups showed short-term improvement (immediate reduction in PI post-brushing; GI improvement at week 1). The primary outcome showed no significant between-group difference in ΔPI from baseline to week 1. Secondary analyses similarly found no significant between-group differences in ΔPI or ΔGI at month 1. Conclusions In a population with high baseline oral-hygiene proficiency, adding PDA did not confer a measurable advantage over standardized instruction alone on PI or GI change. PDA may be more informative in lay populations with lower oral-health literacy. Trial registration ClinicalTrials.gov, NCT06080672, registered on October 12, 2023.
dc.identifier.citationBallı Akgöl, B., Bayram, M., Üstün, N., & Aksaka, N. (2026). Effect of plaque-disclosing agents on biofilm removal: Single-center randomized trial in fourth-year dental students. Head & Face Medicine, 22(1), pp. 1-11. https://doi.org/10.1186/s13005-026-00596-z
dc.identifier.doi10.1186/s13005-026-00596-z
dc.identifier.endpage11
dc.identifier.issn1746-160X
dc.identifier.issue1
dc.identifier.pmidPMID: 41792751
dc.identifier.scopus2-s2.0-105034635011
dc.identifier.scopusqualityQ2
dc.identifier.startpage1
dc.identifier.urihttps://doi.org/10.1186/s13005-026-00596-z
dc.identifier.urihttps://hdl.handle.net/20.500.13055/1399
dc.identifier.volume22
dc.identifier.wosWOS:001732104400001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynak.otherSCI-E - Science Citation Index Expanded
dc.institutionauthorÜstün, Nilüfer
dc.institutionauthorid0000-0001-5489-6883
dc.language.isoen
dc.publisherBioMed Central
dc.relation.ispartofHead & Face Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPlaque-Disclosing Agents
dc.subjectDental Education
dc.subjectPlaque Index
dc.subjectGingival Index
dc.subjectOral Hygiene
dc.titleEffect of plaque-disclosing agents on biofilm removal: Single-center randomized trial in fourth-year dental students
dc.typeArticle
dspace.entity.typePublication

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