Clinical significance of coronary artery tortuosity in chronic coronary syndrome & stable angina: Insights from gensini scores

dc.authorid0000-0002-3895-1923
dc.authorid0000-0001-5227-1716
dc.authorid0000-0002-2753-1528
dc.authorid0000-0001-8206-8268
dc.authorid0000-0001-8862-750X
dc.contributor.authorÖzyaşar, Mehmet
dc.contributor.authorDoğduş, Mustafa
dc.contributor.authorYılmaz, Ahmet
dc.contributor.authorAltıntaş, Mehmet Sait
dc.contributor.authorYetkin, Ertan
dc.date.accessioned2024-10-30T09:16:15Z
dc.date.available2024-10-30T09:16:15Z
dc.date.issued2024
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractOBJECTIVE This study investigated the clinical significance of coronary artery tortuosity (CAT) in chronic coronary syndrome (CCS) by using Gensini scores. METHODS The retrospective single-center study involved 388 patients undergoing coronary angiography for chest pain, excluding those with acute coronary syndromes or prior coronary interventions. Demographic, clinical, and angiographic data were collected and categorized based on the presence or absence of CAT. Categorical variables were analyzed using appropriate statistical tests, with significance set at p < 0.05. RESULTS Analysis of 388 patients revealed that CAT was associated with older age (p <0.001), female gender (p <0.001), lower smoking (19.3% vs. 29.6%, p=0.025), and hypertension (53.5% vs. 38.7%, p=0.05). There was a slightly higher, nearly significant, prevalence of diabetes in the CAT group (22.8% vs. 14.5%, p=0.051). Furthermore, CAT correlated with diastolic dysfunction (p=0.04) and inversely with coronary atherosclerosis severity, as indicated by lower Gensini scores correlating with higher CAT scores (p=0.039 and p=0.049, respectively). Univariate analysis confirmed CAT's association with older age (p <0,001), female gender (p <0,001), hypertension (p=0,004), diabetes (p=0,039), diastolic dysfunction (p=0,003), and Gensini score (p=0,012). Multivariate analysis further identified significant correlations with age (p=0,001), female gender (p <0,001), and Gensini score (p=0,049). CONCLUSIONS Our findings indicate that older age and female gender predict CAT development in CCS patients. The lower Gensini scores associated with CAT may possibly be due to a reduced atherosclerotic plaque burden in these patients. Further research into this relationship could inform the development of treatment and management strategies for coronary atherosclerosis.
dc.identifier.citationÖzyaşar, M., Doğduş, M., Yılmaz, A., Altıntaş, M. S., & Yetkin, E. (2024). Clinical significance of coronary artery tortuosity in chronic coronary syndrome & stable angina: Insights from gensini scores. Archives of the Turkish Society of Cardiology, 52(8). https://doi.org/10.5543/tkda.2024.87425
dc.identifier.doi10.5543/tkda.2024.87425
dc.identifier.issn1016-5169
dc.identifier.issn1308-4488
dc.identifier.issue8
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.5543/tkda.2024.87425
dc.identifier.urihttps://hdl.handle.net/20.500.13055/835
dc.identifier.volume52
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynak.otherESCI - Emerging Sources Citation Index
dc.institutionauthorYetkin, Ertan
dc.institutionauthorid0000-0001-8862-750X
dc.language.isoen
dc.publisherKare Publishing
dc.relation.ispartofArchives of the Turkish Society of Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectChronic Coronary Syndrome
dc.subjectCoronary Artery Tortuosity
dc.subjectGensini Score
dc.titleClinical significance of coronary artery tortuosity in chronic coronary syndrome & stable angina: Insights from gensini scores
dc.typeArticle
dspace.entity.typePublication

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