Modeling the health economic burden of hepatitis C virus infection in Turkey: Cost-effectiveness of targeted screening

dc.authorscopusid58645671800en_US
dc.authorwosidFRR-6566-2022en_US
dc.contributor.authorÇekin, Ayhan Hilmi
dc.contributor.authorGüner, Rahmet
dc.contributor.authorİnkaya, Ahmet Çağkan
dc.contributor.authorOğuz, Dilek
dc.contributor.authorÖzdemir, Oktay
dc.contributor.authorTabak, Ömer Fehmi
dc.date.accessioned2023-08-14T07:39:06Z
dc.date.available2023-08-14T07:39:06Z
dc.date.issued2023en_US
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıp Eğitimi Ana Bilim Dalıen_US
dc.description.abstractBackground/Aims: In 2016, World Health Organization introduced global goals to eliminate hepatitis C virus by 2030. The aim of this study is to analyze the epidemiologic and economic burden of hepatitis C virus in Turkey and compare current practice (regular care) with a hypothetical active screening and treatment approach (active scenario). Materials and Methods: A Markov model was used to analyze and compare regular care with a scenario developed by experts including the screening and treatment of all acute and chronic hepatitis C virus infections between 2020 and 2050. General and targeted populations were focused. The model reflected the natural history of the disease, and the inputs were based on a literature review and expert opinions. Costs were provided by previous studies and national regulations. Results: The active scenario resulted in higher spending for all groups compared with regular care in the first year. Cumulative costs were equalized in the 8th, 12th, 13th, and 16th year and followed by cost-savings of 49.7 million, 1.1 billion, 288.6 million, and 883.4 million Turkish liras in 20 years for prisoners, refugees, people who inject drugs (PWID), and all population, respectively. In all groups, the mortality was found to be lower with the active scenario. In total, 62.8% and 50.6% of expected deaths with regular care in 5 and 20 years, respectively, were prevented with the active scenario. Conclusions: An active screening and treatment approach for hepatitis C virus infection could be cost-effective for PWID, prisoners, and refugees. Almost two-thirds of deaths in regular care could be prevented in 5 years’ time with this approach.en_US
dc.identifier.citationÇekin, A. H., Güner, R., İnkaya, A. Ç., Oğuz, D., Özdemir, O., & Tabak, Ö. F. (2023). Modeling the health economic burden of hepatitis C virus infection in Turkey: Cost-effectiveness of targeted screening. Turkish Journal of Gastroenterology, 34(10), pp. 1062-1070. https://doi.org/10.5152/tjg.2023.22749en_US
dc.identifier.doi10.5152/tjg.2023.22749en_US
dc.identifier.endpage1070en_US
dc.identifier.issn2148-5607
dc.identifier.issue10en_US
dc.identifier.pmidPMID: 37565793en_US
dc.identifier.scopus2-s2.0-85174080280en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1062en_US
dc.identifier.trdizinid1241568
dc.identifier.urihttps://doi.org/10.5152/tjg.2023.22749
dc.identifier.urihttps://hdl.handle.net/20.500.13055/525
dc.identifier.volume34en_US
dc.identifier.wosWOS:001101965800009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynak.otherSCI-E - Science Citation Index Expandeden_US
dc.institutionauthorÖzdemir, Oktay
dc.language.isoenen_US
dc.publisherAVESen_US
dc.relation.ispartofTurkish Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHepatitis Cen_US
dc.subjectModel of Careen_US
dc.subjectHealth Policyen_US
dc.subjectEconomic Burdenen_US
dc.subjectDisease Burdenen_US
dc.subjectScreeningen_US
dc.titleModeling the health economic burden of hepatitis C virus infection in Turkey: Cost-effectiveness of targeted screeningen_US
dc.typeArticleen_US
dspace.entity.typePublication

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