The effect of maternal period nutritional status on oro‑sensorial fat perception and taste preference in rats
Yükleniyor...
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
CD36 and GPR120 play an important role in the perception and preference for fat-rich food consumption. We aimed to investigate the relationship between oro-gustatory perception of lipids, fatty taste preference, and maternal (Gestation+Lactation)- maturation period nutrition status in ofspring Sprague–Dawley rats. In our study, mother rats were fed with control (C) or high-fat diets (HFD) during gestation (21 days) and lactation (21 days) periods. After weaning, the ofspring were fed with control (C) or high-fat diets (HFD) during the maturation (120 days) period. Daily calorie intake and weekly body weight measurements were monitored. Two-bottle preference (TBPT) and licking tests measured the fat perceptions and preferences. Plasma levels of insulin, leptin, glucose, and triglyceride were measured. The protein and mRNA expressions of CD36 and GPR120 in the circumvallate papillae (CVP) were determined. The 48 h TBPT results revealed that maternal HFD-exposed ofspring rats signifcantly preferred 2% rapeseed oil solution regardless of the type of maturation diet. According to the licking test, C/C group (C diet exposed group in maternal and maturation periods) ofspring licked 0.1% oleic acid-containing water more than C/HFD (C diet exposed in maternal period and HFD exposed group in maturation period) and HFD/HFD group. (HFD exposed group in maternal and maturation periods) groups. Plasma insulin and leptin concentrations signifcantly increased in HFD/HFD groups compared to C/C group. CD36 protein expressions were signifcantly lower in HFD/ HFD than C/HFD and HFD/C groups. GPR120 and GNAT3 mRNA expressions in HFD/C group were signifcantly higher than in C/HFD group. Our results suggest that HFD exposure during maternal and maturation period may play a role in fat perception/preference through oral lipid sensors.
Açıklama
Anahtar Kelimeler
Maternal Diet, Fatty Taste Preference, CD36, GPR120
Kaynak
Molecular and Cellular Biochemistry
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
478
Sayı
12
Künye
Günalan, E., Karagöz, M. E., Cıvaş, C. C., Bilgin, V. A., Erdoğan, C. S., Güven, A., Yılmaz, B., & Gemici, B. (2023). The effect of maternal period nutritional status on oro‑sensorial fat perception and taste preference in rats. Molecular and Cellular Biochemistry, 478(12), pp. 2861-2873. https://doi.org/10.1007/s11010-023-04703-5
