Liver stiffness and steatosis measurements with iLivTouch and FibroScan: A comparative study

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dc.authorid0000-0002-0335-2330en_US
dc.authorid0000-0002-8909-2102en_US
dc.authorscopusid57478196200en_US
dc.authorscopusid56035868800en_US
dc.authorwosidHIR-7894-2022en_US
dc.authorwosidK-1194-2018en_US
dc.contributor.authorÖzercan, Mübin
dc.contributor.authorMelekoğlu Ellik, Zeynep
dc.contributor.authorParmaksız, Ayhan
dc.contributor.authorGümüşsoy, Mesut
dc.contributor.authorDuman, Serkan
dc.contributor.authorÖrmeci, Necati
dc.date.accessioned2024-07-05T06:10:26Z
dc.date.available2024-07-05T06:10:26Z
dc.date.issued2024en_US
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyoistatistik Ana Bilim Dalıen_US
dc.description.abstractBackground/Aims: The presence of liver fibrosis is the most important indicator of progression to cirrhosis. Noninvasive measurement of liver stiffness is crucial for detecting fibrosis. Vibration-controlled transient elastography is one of the most useful methods for this pur%02pose. We aimed to compare the liver stiffness and steatosis measurements with iLivTouch© and the FibroScan© elastography devices Materials and Methods: Two hundred thirty-seven consecutive adult patients with chronic hepatitis were included in the study. The liver stiffness and steatosis were measured with iLivTouch and FibroScan on the same day. Thirty-one patients had liver biopsies on the same day with elastography procedures. The diagnostic performances of iLivTouch and FibroScan were compared to aspartate aminotrans%02ferase to platelet ratio index (APRI), Fibrosis-4 (FIB-4), and nonalcoholic fatty liver disease fibrosis score (NFS). Results: The liver stiffness measurements obtained using iLivTouch and FibroScan had median value of 10.3 (ranging from 2.9 to 46.3) and 7.2 (ranging from 2.5 to 75), respectively. The mean steatosis measurements using ultrasound attenuation parameter with iLiv%02Touch were 245.51 ± 45.79, while the mean controlled attenuation parameter measurements using FibroScan were 259.37 ± 75.0. In subgroup analysis, the AUC of iLivTouch on detecting signiicant fibrosis [0.83, (P = .002)] was minimally higher than other noninvasive methods [0.82 for NFS (P = .003), 0.80 for FibroScan (P = .006), 0.68 for FIB-4 (P = .089), and 0.53 for APRI (P = .76)]. Conclusion: The stiffness and steatosis measurements with iLivTouch and FibroScan were not similar. The accuracy of iLivTouch in detecting significant and advanced fibrosis was minimally higher. Large clinical trials are necessary to support these findings.en_US
dc.identifier.citationÖzercan, M., Melekoğlu Ellik, Z., Parmaksız, A., Gümüşsoy, M., Duman, S., & Örmeci, N. (2024). Liver stiffness and steatosis measurements with iLivTouch and FibroScan: A comparative study. Turkish Journal of Gastroenterology, 35(8), pp. 634-642. https://doi.org/10.5152/tjg.2024.23531en_US
dc.identifier.doi10.5152/tjg.2024.23531en_US
dc.identifier.endpage642en_US
dc.identifier.issn2148-5607
dc.identifier.issue8en_US
dc.identifier.pmidPMID: 39150398en_US
dc.identifier.scopus2-s2.0-85201515411en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage634en_US
dc.identifier.urihttps://doi.org/10.5152/tjg.2024.23531
dc.identifier.urihttps://hdl.handle.net/20.500.13055/732
dc.identifier.volume35en_US
dc.identifier.wosWOS:001318111800006
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynak.otherSCI-E - Science Citation Index Expandeden_US
dc.institutionauthorParmaksız, Ayhan
dc.institutionauthorÖrmeci, Necati
dc.language.isoenen_US
dc.publisherTurkish Society of Gastroenterologyen_US
dc.relation.ispartofTurkish Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectElastographyen_US
dc.subjectiLivTouchen_US
dc.subjectFibroScanen_US
dc.subjectStiffnessen_US
dc.subjectSteatosisen_US
dc.titleLiver stiffness and steatosis measurements with iLivTouch and FibroScan: A comparative studyen_US
dc.typeArticleen_US
dspace.entity.typePublication

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